Revealing the potential role of hsa-miR-663a in modulating the PI3K-Akt signaling pathway via miRNA microarray in spinal muscular atrophy patient fibroblast-derived iPSCs
Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disorder due to deletion or mutation of survival motor neuron 1 (SMN1) gene. Although survival motor neuron 2 (SMN2) gene is still present in SMA patients, the production of full-length survival motor neuron (SMN) protein is insuf...
Main Authors: | Gandhi, Gayatri, Kodiappan, Radha, Abdullah, Syahril, Teoh, Hoon Koon, Tai, Lihui, Cheong, Soon Keng, Yeo, Wendy Wai Yeng |
---|---|
Format: | Article |
Language: | English |
Published: |
Oxford University Press
2024
|
Online Access: | http://psasir.upm.edu.my/id/eprint/114222/1/114222.pdf |
Similar Items
-
Importance of miRNA stability and alternative primary miRNA isoforms in gene regulation during Drosophila development
by: Zhou, Li, et al.
Published: (2018) -
Scaffold-mediated sustained, non-viral delivery of miR-219/miR-338 promotes CNS remyelination
by: Milbreta, Ulla, et al.
Published: (2020) -
Mapping miRNA research in schizophrenia: a scientometric review
by: Lim, Mengyu, et al.
Published: (2023) -
Different modes of regulation govern miRNA expression levels in Drosophila melanogaster
by: Lim, Mandy Yu Theng
Published: (2019) -
Tissue-specific modulation of CRISPR activity by miRNA-sensing guide RNAs
by: Garcia-Guerra, A, et al.
Published: (2025)