Effects of methanol on the synthesis of aspartame precursor catalysed by Pseudomonas aeruginosa elastase
Pseudomonas elastase was found to be efficient in catalysing the reaction between N-benzyloxycarbonyl-L-aspartic acid and L-phenylalanine methyl ester producing the aspartame precursor in aqueous and aqueous methanolic solutions. 25% (v/v) methanol was most favourable for the synthesis where about 1...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Kluwer Academic Publishers
1992
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| Online Access: | http://psasir.upm.edu.my/id/eprint/114968/1/114968.pdf |
| Summary: | Pseudomonas elastase was found to be efficient in catalysing the reaction between N-benzyloxycarbonyl-L-aspartic acid and L-phenylalanine methyl ester producing the aspartame precursor in aqueous and aqueous methanolic solutions. 25% (v/v) methanol was most favourable for the synthesis where about 100% increase in yield was obtained compared to that in aqueous solution. |
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