Glutathione S-transferase and gamma-glutamyl transpeptidase activities in cultured rat hepatocytes treated with tocotrienol and tocopherol
1. The effect of tocotrienol and tocopherol on glutathione S-transferase (GST) and gammaglutamyl transpeptidase (GGT) activities in cultured rat hepatocytes were investigated. 2. Tocotrienol and tocopherol significantly decreased GGT activities at 5 days in culture but tocotrienol also significantly...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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1993
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| Online Access: | http://psasir.upm.edu.my/id/eprint/115052/1/115052.pdf |
| _version_ | 1824452516438343680 |
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| author | Ong, F.B. Wan Ngah, W.Z. Shamaan, N.A. Md. Top, A.G. Marzuki, A. Khalid, A.K. |
| author_facet | Ong, F.B. Wan Ngah, W.Z. Shamaan, N.A. Md. Top, A.G. Marzuki, A. Khalid, A.K. |
| author_sort | Ong, F.B. |
| collection | UPM |
| description | 1. The effect of tocotrienol and tocopherol on glutathione S-transferase (GST) and gammaglutamyl transpeptidase (GGT) activities in cultured rat hepatocytes were investigated. 2. Tocotrienol and tocopherol significantly decreased GGT activities at 5 days in culture but tocotrienol also significantly decreased GGT activities at 1-2 days. 3. Tocotrienol and tocopherol treatment significantly decreased GST activities at 3 days compared to the control but tocotrienol also decreased GST activities at 1-3 days. 4. Tocotrienol showed a more pronounced effect at a dosage of greater than 50 μM tocotrienol at 1-3 days in culture compared to the control. © 1993. |
| first_indexed | 2025-02-19T02:51:46Z |
| format | Article |
| id | upm.eprints-115052 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2025-02-19T02:51:46Z |
| publishDate | 1993 |
| record_format | dspace |
| spelling | upm.eprints-1150522025-02-18T07:00:11Z http://psasir.upm.edu.my/id/eprint/115052/ Glutathione S-transferase and gamma-glutamyl transpeptidase activities in cultured rat hepatocytes treated with tocotrienol and tocopherol Ong, F.B. Wan Ngah, W.Z. Shamaan, N.A. Md. Top, A.G. Marzuki, A. Khalid, A.K. 1. The effect of tocotrienol and tocopherol on glutathione S-transferase (GST) and gammaglutamyl transpeptidase (GGT) activities in cultured rat hepatocytes were investigated. 2. Tocotrienol and tocopherol significantly decreased GGT activities at 5 days in culture but tocotrienol also significantly decreased GGT activities at 1-2 days. 3. Tocotrienol and tocopherol treatment significantly decreased GST activities at 3 days compared to the control but tocotrienol also decreased GST activities at 1-3 days. 4. Tocotrienol showed a more pronounced effect at a dosage of greater than 50 μM tocotrienol at 1-3 days in culture compared to the control. © 1993. 1993 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/115052/1/115052.pdf Ong, F.B. and Wan Ngah, W.Z. and Shamaan, N.A. and Md. Top, A.G. and Marzuki, A. and Khalid, A.K. (1993) Glutathione S-transferase and gamma-glutamyl transpeptidase activities in cultured rat hepatocytes treated with tocotrienol and tocopherol. Comparative Biochemistry and Physiology. Part C: Comparative, 106 (1). pp. 237-240. ISSN 0742-8413; eISSN: 0742-8413 https://linkinghub.elsevier.com/retrieve/pii/074284139390277R 10.1016/0742-8413(93)90277-R |
| spellingShingle | Ong, F.B. Wan Ngah, W.Z. Shamaan, N.A. Md. Top, A.G. Marzuki, A. Khalid, A.K. Glutathione S-transferase and gamma-glutamyl transpeptidase activities in cultured rat hepatocytes treated with tocotrienol and tocopherol |
| title | Glutathione S-transferase and gamma-glutamyl transpeptidase activities in cultured rat hepatocytes treated with tocotrienol and tocopherol |
| title_full | Glutathione S-transferase and gamma-glutamyl transpeptidase activities in cultured rat hepatocytes treated with tocotrienol and tocopherol |
| title_fullStr | Glutathione S-transferase and gamma-glutamyl transpeptidase activities in cultured rat hepatocytes treated with tocotrienol and tocopherol |
| title_full_unstemmed | Glutathione S-transferase and gamma-glutamyl transpeptidase activities in cultured rat hepatocytes treated with tocotrienol and tocopherol |
| title_short | Glutathione S-transferase and gamma-glutamyl transpeptidase activities in cultured rat hepatocytes treated with tocotrienol and tocopherol |
| title_sort | glutathione s transferase and gamma glutamyl transpeptidase activities in cultured rat hepatocytes treated with tocotrienol and tocopherol |
| url | http://psasir.upm.edu.my/id/eprint/115052/1/115052.pdf |
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