Candida glabrata gene expression response upon engulfment by THP-1 macrophages
Candida glabeuta has emerged as a significant pathogen, particularly in immunocompromised individuals. It exhibits a unique capability to persist within macrophages, thereby prolonging the infection. This study investigates the alteration of ICLI and MNN2 gene expression in engulfed C glabrata durin...
| Main Authors: | , |
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| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
2024
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| Online Access: | http://psasir.upm.edu.my/id/eprint/115493/1/115493.jpg |
| _version_ | 1825940676425023488 |
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| author | Ismail, Elysha Nur Than, Leslie Thian Lung |
| author_facet | Ismail, Elysha Nur Than, Leslie Thian Lung |
| author_sort | Ismail, Elysha Nur |
| collection | UPM |
| description | Candida glabeuta has emerged as a significant pathogen, particularly in immunocompromised individuals. It exhibits a unique capability to persist within macrophages, thereby prolonging the infection. This study investigates the alteration of ICLI and MNN2 gene expression in engulfed C glabrata during macrophage interaction to understand its adaptive strategies against the host immune system, specifically focusing on genes linked to altered metabolism and cell wall modifications. The rise in multidrug-resistant C. globroto strains limits treatment options, necessitating a congrefensive understanding of its gone functions and interactions. |
| first_indexed | 2025-03-07T13:05:26Z |
| format | Conference or Workshop Item |
| id | upm.eprints-115493 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2025-03-07T13:05:26Z |
| publishDate | 2024 |
| record_format | dspace |
| spelling | upm.eprints-1154932025-03-06T02:25:48Z http://psasir.upm.edu.my/id/eprint/115493/ Candida glabrata gene expression response upon engulfment by THP-1 macrophages Ismail, Elysha Nur Than, Leslie Thian Lung Candida glabeuta has emerged as a significant pathogen, particularly in immunocompromised individuals. It exhibits a unique capability to persist within macrophages, thereby prolonging the infection. This study investigates the alteration of ICLI and MNN2 gene expression in engulfed C glabrata during macrophage interaction to understand its adaptive strategies against the host immune system, specifically focusing on genes linked to altered metabolism and cell wall modifications. The rise in multidrug-resistant C. globroto strains limits treatment options, necessitating a congrefensive understanding of its gone functions and interactions. 2024 Conference or Workshop Item PeerReviewed image en http://psasir.upm.edu.my/id/eprint/115493/1/115493.jpg Ismail, Elysha Nur and Than, Leslie Thian Lung (2024) Candida glabrata gene expression response upon engulfment by THP-1 macrophages. In: 14th Malaysian Symposium of Biomedical Science 2024, 1-2 Jun. 2024, Universiti Putra Malaysia, Serdang. . (Submitted) |
| spellingShingle | Ismail, Elysha Nur Than, Leslie Thian Lung Candida glabrata gene expression response upon engulfment by THP-1 macrophages |
| title | Candida glabrata gene expression response upon engulfment by THP-1 macrophages |
| title_full | Candida glabrata gene expression response upon engulfment by THP-1 macrophages |
| title_fullStr | Candida glabrata gene expression response upon engulfment by THP-1 macrophages |
| title_full_unstemmed | Candida glabrata gene expression response upon engulfment by THP-1 macrophages |
| title_short | Candida glabrata gene expression response upon engulfment by THP-1 macrophages |
| title_sort | candida glabrata gene expression response upon engulfment by thp 1 macrophages |
| url | http://psasir.upm.edu.my/id/eprint/115493/1/115493.jpg |
| work_keys_str_mv | AT ismailelyshanur candidaglabratageneexpressionresponseuponengulfmentbythp1macrophages AT thanlesliethianlung candidaglabratageneexpressionresponseuponengulfmentbythp1macrophages |