In Vivo And In Vitro Studies Of Anti-Cholesterol And Anti-Carcinogenic Effects Of Ganoderma Crud Extract

The in vivo and in vitro effect of a local, commercially available Ganoderma fruiting body powder (GF) and G. lucidum mycelium (GM) grown in soy waste on tumour and hypercholesterolaemic rats were studied. Administration of 1 % cholesterol diet in the cholesterol (Chol) group caused a significant...

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Main Author: Choong, Yew Keong
Format: Thesis
Language:English
English
Published: 2003
Subjects:
Online Access:http://psasir.upm.edu.my/id/eprint/11674/1/FSAS_2003_47.pdf
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author Choong, Yew Keong
author_facet Choong, Yew Keong
author_sort Choong, Yew Keong
collection UPM
description The in vivo and in vitro effect of a local, commercially available Ganoderma fruiting body powder (GF) and G. lucidum mycelium (GM) grown in soy waste on tumour and hypercholesterolaemic rats were studied. Administration of 1 % cholesterol diet in the cholesterol (Chol) group caused a significant (p<O.05) increase in the serum total cholesterol (TC), triglyceride (TG) and low density lipoprotein cholesterol (LDL-C) levels while reducing serum high density lipoprotein cholesterol (HDL-C) level. In the case of the Chol+GF and Chol+GM groups, the initial serum TC, TG and LDL-C levels showed a much higher levels (p<O.05) compared to the Chol group. However, the levels gradually decreased towards the end of the experiment. There was no significant difference in the lipid profiles amongst the Control, GF and GM groups. Serum alanine transferase (AL T), gamma glutamyltransferase (GGT) and creatine kinase (CK) in the Chol+GF group as well as the AL T, GGT level in the
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spelling upm.eprints-116742024-06-24T08:14:45Z http://psasir.upm.edu.my/id/eprint/11674/ In Vivo And In Vitro Studies Of Anti-Cholesterol And Anti-Carcinogenic Effects Of Ganoderma Crud Extract Choong, Yew Keong The in vivo and in vitro effect of a local, commercially available Ganoderma fruiting body powder (GF) and G. lucidum mycelium (GM) grown in soy waste on tumour and hypercholesterolaemic rats were studied. Administration of 1 % cholesterol diet in the cholesterol (Chol) group caused a significant (p<O.05) increase in the serum total cholesterol (TC), triglyceride (TG) and low density lipoprotein cholesterol (LDL-C) levels while reducing serum high density lipoprotein cholesterol (HDL-C) level. In the case of the Chol+GF and Chol+GM groups, the initial serum TC, TG and LDL-C levels showed a much higher levels (p<O.05) compared to the Chol group. However, the levels gradually decreased towards the end of the experiment. There was no significant difference in the lipid profiles amongst the Control, GF and GM groups. Serum alanine transferase (AL T), gamma glutamyltransferase (GGT) and creatine kinase (CK) in the Chol+GF group as well as the AL T, GGT level in the 2003-04 Thesis NonPeerReviewed text en http://psasir.upm.edu.my/id/eprint/11674/1/FSAS_2003_47.pdf Choong, Yew Keong (2003) In Vivo And In Vitro Studies Of Anti-Cholesterol And Anti-Carcinogenic Effects Of Ganoderma Crud Extract. Doctoral thesis, Universiti Putra Malaysia. Ganoderma Carcinogens English
spellingShingle Ganoderma
Carcinogens
Choong, Yew Keong
In Vivo And In Vitro Studies Of Anti-Cholesterol And Anti-Carcinogenic Effects Of Ganoderma Crud Extract
title In Vivo And In Vitro Studies Of Anti-Cholesterol And Anti-Carcinogenic Effects Of Ganoderma Crud Extract
title_full In Vivo And In Vitro Studies Of Anti-Cholesterol And Anti-Carcinogenic Effects Of Ganoderma Crud Extract
title_fullStr In Vivo And In Vitro Studies Of Anti-Cholesterol And Anti-Carcinogenic Effects Of Ganoderma Crud Extract
title_full_unstemmed In Vivo And In Vitro Studies Of Anti-Cholesterol And Anti-Carcinogenic Effects Of Ganoderma Crud Extract
title_short In Vivo And In Vitro Studies Of Anti-Cholesterol And Anti-Carcinogenic Effects Of Ganoderma Crud Extract
title_sort in vivo and in vitro studies of anti cholesterol and anti carcinogenic effects of ganoderma crud extract
topic Ganoderma
Carcinogens
url http://psasir.upm.edu.my/id/eprint/11674/1/FSAS_2003_47.pdf
work_keys_str_mv AT choongyewkeong invivoandinvitrostudiesofanticholesterolandanticarcinogeniceffectsofganodermacrudextract