Appropriate Drying And Storage Conditions Of Hempedu Bumi (Andrographis Paniculata Nees)

In this study, the forced air thin layer dryer was used for determining the appropriate drying condition of Andrographis paniculata. The quality of dehydrated A.paniculata was evaluated with andrographolide as reference compound. High performance liquid chromatography was used for the determinati...

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Main Author: Chong, Gun Hean
Format: Thesis
Language:English
English
Published: 2002
Subjects:
Online Access:http://psasir.upm.edu.my/id/eprint/12073/1/FK_2002_39.pdf
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author Chong, Gun Hean
author_facet Chong, Gun Hean
author_sort Chong, Gun Hean
collection UPM
description In this study, the forced air thin layer dryer was used for determining the appropriate drying condition of Andrographis paniculata. The quality of dehydrated A.paniculata was evaluated with andrographolide as reference compound. High performance liquid chromatography was used for the determination of andrographolide contained in A.paniculata. A suitable storage condition for preserving andrographolide in ground dried A.paniculata was also determined over a three-month storage study period. Three drying temperatures (55, 65 and 75°C) and air velocities (1.0, 1.5 and 2.0m/s) were utilized for the drying experiment with the observed air relative humidity of 66-80%. Drying temperature was found to be an important parameter affecting the drying time and the quality of A.paniculata. The andrographolide content was reduced by 37.54, 53.59 and 62.72% from the initial amount (17.5 ± 3.4 % wt/dry wt) for the drying temperatures of 55, 65 and 75°C, respectively. However, from the heating cost point of view, 75°C temperature and 1.0m/s air velocity was the appropriate drying condition for A.paniculata. since the cost per unit andrographolide remaining for that drying temperature was the lowest. On the other hand. a larger amount of andrographolide can be maintained with drying condition of 55°C drying temperature and 1.0m/s air velocity. Andrographolide was satisfactorily maintained at three selected storage conditions (5±2°C; 25±2°C with 60±5% RH; 30±2°C with 60±5%RH), which A.paniculata was kept in air tight glass bottle; without any significant reduction of this compound after three months. Therefore, ambient condition (30 ±2°C, 60±5% RH) is acceptable for storage of A.paniculata with respect to andrographolide preservation.
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spelling upm.eprints-120732024-06-28T00:43:24Z http://psasir.upm.edu.my/id/eprint/12073/ Appropriate Drying And Storage Conditions Of Hempedu Bumi (Andrographis Paniculata Nees) Chong, Gun Hean In this study, the forced air thin layer dryer was used for determining the appropriate drying condition of Andrographis paniculata. The quality of dehydrated A.paniculata was evaluated with andrographolide as reference compound. High performance liquid chromatography was used for the determination of andrographolide contained in A.paniculata. A suitable storage condition for preserving andrographolide in ground dried A.paniculata was also determined over a three-month storage study period. Three drying temperatures (55, 65 and 75°C) and air velocities (1.0, 1.5 and 2.0m/s) were utilized for the drying experiment with the observed air relative humidity of 66-80%. Drying temperature was found to be an important parameter affecting the drying time and the quality of A.paniculata. The andrographolide content was reduced by 37.54, 53.59 and 62.72% from the initial amount (17.5 ± 3.4 % wt/dry wt) for the drying temperatures of 55, 65 and 75°C, respectively. However, from the heating cost point of view, 75°C temperature and 1.0m/s air velocity was the appropriate drying condition for A.paniculata. since the cost per unit andrographolide remaining for that drying temperature was the lowest. On the other hand. a larger amount of andrographolide can be maintained with drying condition of 55°C drying temperature and 1.0m/s air velocity. Andrographolide was satisfactorily maintained at three selected storage conditions (5±2°C; 25±2°C with 60±5% RH; 30±2°C with 60±5%RH), which A.paniculata was kept in air tight glass bottle; without any significant reduction of this compound after three months. Therefore, ambient condition (30 ±2°C, 60±5% RH) is acceptable for storage of A.paniculata with respect to andrographolide preservation. 2002-10 Thesis NonPeerReviewed text en http://psasir.upm.edu.my/id/eprint/12073/1/FK_2002_39.pdf Chong, Gun Hean (2002) Appropriate Drying And Storage Conditions Of Hempedu Bumi (Andrographis Paniculata Nees). Masters thesis, Universiti Putra Malaysia. Andrographis English
spellingShingle Andrographis
Chong, Gun Hean
Appropriate Drying And Storage Conditions Of Hempedu Bumi (Andrographis Paniculata Nees)
title Appropriate Drying And Storage Conditions Of Hempedu Bumi (Andrographis Paniculata Nees)
title_full Appropriate Drying And Storage Conditions Of Hempedu Bumi (Andrographis Paniculata Nees)
title_fullStr Appropriate Drying And Storage Conditions Of Hempedu Bumi (Andrographis Paniculata Nees)
title_full_unstemmed Appropriate Drying And Storage Conditions Of Hempedu Bumi (Andrographis Paniculata Nees)
title_short Appropriate Drying And Storage Conditions Of Hempedu Bumi (Andrographis Paniculata Nees)
title_sort appropriate drying and storage conditions of hempedu bumi andrographis paniculata nees
topic Andrographis
url http://psasir.upm.edu.my/id/eprint/12073/1/FK_2002_39.pdf
work_keys_str_mv AT chonggunhean appropriatedryingandstorageconditionsofhempedubumiandrographispaniculatanees