Andrographolide inhibits growth of acute promyelocytic leukaemia cells by inducing retinoic acid receptor-independent cell differentiation and apoptosis
OBJECTIVES: The growth inhibiting potential of andrographolide was evaluated in three acute promyelocytic leukaemia cell line models (HL-60, NB4 and all-trans retinoic acid (ATRA)-resistant NB4-R2). METHODS: In elucidating the mechanisms of growth inhibition, a special emphasis was placed on assess...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
John Wiley & Sons
2009
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| Online Access: | http://psasir.upm.edu.my/id/eprint/13109/1/Andrographolide%20inhibits%20growth%20of%20acute%20promyelocytic%20leukaemia%20cells%20by%20inducing%20retinoic%20acid%20receptor.pdf |