Anti-inflammatory and antinociceptive activities of the ethanolic extract of Pluchea indica (L) less leaf
Ethanolic extract of Pluchea indica leaf (PIL) was used to investigate its anti-inflammatory and antinociceptive activities by using carrageenan - induced oedema model and acetic acid induced writhing test. PIL exhibited significant and dose-dependent anti-inflammatory activity at a dose of 300 mg/k...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Società Italo-Latinoamericana di Etnomedicina
2008
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| Online Access: | http://psasir.upm.edu.my/id/eprint/13149/1/Anti-inflammatory%20and%20antinociceptive%20activities%20of%20the%20ethanolic%20extract%20of%20Pluchea%20indica%20%28L%29%20less%20leaf.pdf |
| Summary: | Ethanolic extract of Pluchea indica leaf (PIL) was used to investigate its anti-inflammatory and antinociceptive activities by using carrageenan - induced oedema model and acetic acid induced writhing test. PIL exhibited significant and dose-dependent anti-inflammatory activity at a dose of 300 mg/kg when administered orally. It is also demonstrated that the i.p administration of PIL at a dose of 10, 30, 100 and 300 mg/kg produced significant inhibition of abdominal constriction induced with 0.6% (v/v) acetic acid in dose dependent manner. These results indicate that PIL exhibits significant anti-inflammatory and antinociceptive effects. |
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