Assessment of P-gp and MRP1 activities using MultiDrugQuant Assay Kit : a preliminary study of correlation between protein expressions and its functional activities in newly diagnosed acute leukaemia patients.

Assessment of P-gp and MRP1 activities using MultiDrugQuant Assay Kit : a preliminary study of correlation between protein expressions and its functional activities in newly diagnosed acute leukaemia patients.

Multidrug resistance (MDR) is believed to be responsible for poor response of patients towards chemotherapy particularly patients with acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). The best-characterized resistance mechanism is the one mediated by permeability-glycoprotein (P-...

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Bibliographic Details
Main Authors: Nordin, Fazlina, Abdullah, Maha, Abdul Latiff , Zarina, Alias, Hamidah, Syed Zakaria, Syed Zulkifli, Cheong, Soon Keng, Othman, Ainoon, Jamal, Rahman, Noor Hamidah
Format: Article
Language:English
Published: Malaysian Society of Pathologists 2008
Online Access:http://psasir.upm.edu.my/id/eprint/13305/1/Assessment%20of%20P.pdf

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