α-tocopherol nanodispersions : preparation, characterization and stability evaluation.

A top down approach based on emulsification–evaporation technique was used to prepare nanodispersion of α-tocopherol. Physicochemical properties of the prepared nanodispersions were investigated under combination of the processing parameters (pressure and cycle) and ratio of aqueous:organic. Storage...

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Main Authors: Cheong, Jean Ne, Tan, Chin Ping, Che Man, Yaakob, Misran, Misni
Format: Article
Language:English
Published: Elsevier 2008
Online Access:http://psasir.upm.edu.my/id/eprint/13322/1/%CE%B1-tocopherol%20nanodispersions%20%20preparation%2C%20characterization%20and%20stability%20evaluation.pdf
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author Cheong, Jean Ne
Tan, Chin Ping
Che Man, Yaakob
Misran, Misni
author_facet Cheong, Jean Ne
Tan, Chin Ping
Che Man, Yaakob
Misran, Misni
author_sort Cheong, Jean Ne
collection UPM
description A top down approach based on emulsification–evaporation technique was used to prepare nanodispersion of α-tocopherol. Physicochemical properties of the prepared nanodispersions were investigated under combination of the processing parameters (pressure and cycle) and ratio of aqueous:organic. Storage study was performed for 3 months to evaluate the stability of all the prepared nanodispersions. The results showed that homogenization pressure have significant (P < 0.05) influence on the droplet diameter and size distribution. On the contrary, the processing cycle had not significant (P > 0.05) effect on the droplet diameter and size distribution of the prepared nanodispersion. Droplet diameters in the range of 90–120 nm were obtained for the prepared α-tocopherol nanodispersions. During storage duration, there were no significant (P > 0.05) changes in mean diameters while the concentrations of α-tocopherol were significantly (P < 0.05) reduced for all prepared nanodispersions. In general, it is shown that emulsification–evaporation technique can be used as a suitable technique for the production of α-tocopherol nanodispersions with narrow size distribution.
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spelling upm.eprints-133222015-11-24T04:26:31Z http://psasir.upm.edu.my/id/eprint/13322/ α-tocopherol nanodispersions : preparation, characterization and stability evaluation. Cheong, Jean Ne Tan, Chin Ping Che Man, Yaakob Misran, Misni A top down approach based on emulsification–evaporation technique was used to prepare nanodispersion of α-tocopherol. Physicochemical properties of the prepared nanodispersions were investigated under combination of the processing parameters (pressure and cycle) and ratio of aqueous:organic. Storage study was performed for 3 months to evaluate the stability of all the prepared nanodispersions. The results showed that homogenization pressure have significant (P < 0.05) influence on the droplet diameter and size distribution. On the contrary, the processing cycle had not significant (P > 0.05) effect on the droplet diameter and size distribution of the prepared nanodispersion. Droplet diameters in the range of 90–120 nm were obtained for the prepared α-tocopherol nanodispersions. During storage duration, there were no significant (P > 0.05) changes in mean diameters while the concentrations of α-tocopherol were significantly (P < 0.05) reduced for all prepared nanodispersions. In general, it is shown that emulsification–evaporation technique can be used as a suitable technique for the production of α-tocopherol nanodispersions with narrow size distribution. Elsevier 2008 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/13322/1/%CE%B1-tocopherol%20nanodispersions%20%20preparation%2C%20characterization%20and%20stability%20evaluation.pdf Cheong, Jean Ne and Tan, Chin Ping and Che Man, Yaakob and Misran, Misni (2008) α-tocopherol nanodispersions : preparation, characterization and stability evaluation. Journal of Food Engineering, 89 (2). pp. 204-209. ISSN 0260-8774 10.1016/j.jfoodeng.2008.04.018
spellingShingle Cheong, Jean Ne
Tan, Chin Ping
Che Man, Yaakob
Misran, Misni
α-tocopherol nanodispersions : preparation, characterization and stability evaluation.
title α-tocopherol nanodispersions : preparation, characterization and stability evaluation.
title_full α-tocopherol nanodispersions : preparation, characterization and stability evaluation.
title_fullStr α-tocopherol nanodispersions : preparation, characterization and stability evaluation.
title_full_unstemmed α-tocopherol nanodispersions : preparation, characterization and stability evaluation.
title_short α-tocopherol nanodispersions : preparation, characterization and stability evaluation.
title_sort α tocopherol nanodispersions preparation characterization and stability evaluation
url http://psasir.upm.edu.my/id/eprint/13322/1/%CE%B1-tocopherol%20nanodispersions%20%20preparation%2C%20characterization%20and%20stability%20evaluation.pdf
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AT tanchinping atocopherolnanodispersionspreparationcharacterizationandstabilityevaluation
AT chemanyaakob atocopherolnanodispersionspreparationcharacterizationandstabilityevaluation
AT misranmisni atocopherolnanodispersionspreparationcharacterizationandstabilityevaluation