Biological activities of four Melicope species
The leaves and stem barks extracts of four plant species, Melicope confusa, M. clemensiae, M. lunu-ankenda and M. latifolia were screened for their antimicrobial, antioxidant and cytotoxic activities. Almost all extracts of M. clemensia exhibited moderate growth inhibition when tested against the th...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Universiti Kebangsaan Malaysia
2009
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| Online Access: | http://psasir.upm.edu.my/id/eprint/13415/1/Biological%20activities%20of%20four%20Melicope%20species.pdf |
| _version_ | 1825945232138567680 |
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| author | Mohd Hashim, Najihah Rahmani, Mawardi Mohd Ismail, Hazar Bebe Md. Sukari, Mohd. Aspollah Ali, Abdul Manaf Ee, Gwendoline Cheng Lian |
| author_facet | Mohd Hashim, Najihah Rahmani, Mawardi Mohd Ismail, Hazar Bebe Md. Sukari, Mohd. Aspollah Ali, Abdul Manaf Ee, Gwendoline Cheng Lian |
| author_sort | Mohd Hashim, Najihah |
| collection | UPM |
| description | The leaves and stem barks extracts of four plant species, Melicope confusa, M. clemensiae, M. lunu-ankenda and M. latifolia were screened for their antimicrobial, antioxidant and cytotoxic activities. Almost all extracts of M. clemensia exhibited moderate growth inhibition when tested against the three pathogenic fungi. However, when tested against pathogenic bacteria, the three leaves extracts showed strong activity against methicillin resistant S. aureus and moderate for the other bacteria. In the antioxidant assay by using DPPH, the three leaves extracts of M. lunu-ankenda exhibited significant activity with with IC50 values of 7.8, 15.6 and 7.8 μg/mL. In addition, the petroleum ether leaves extract of M. clemensiae and the chloroform leaves extract of M. lunu-ankenda showed strong cytotoxic activity when tested against human promyelocytic leukemia (HL60) cell line with IC50 values of 2.8 and 0.8 μg/mL, respectively. |
| first_indexed | 2024-03-06T07:28:17Z |
| format | Article |
| id | upm.eprints-13415 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T07:28:17Z |
| publishDate | 2009 |
| publisher | Universiti Kebangsaan Malaysia |
| record_format | dspace |
| spelling | upm.eprints-134152015-10-22T04:25:17Z http://psasir.upm.edu.my/id/eprint/13415/ Biological activities of four Melicope species Mohd Hashim, Najihah Rahmani, Mawardi Mohd Ismail, Hazar Bebe Md. Sukari, Mohd. Aspollah Ali, Abdul Manaf Ee, Gwendoline Cheng Lian The leaves and stem barks extracts of four plant species, Melicope confusa, M. clemensiae, M. lunu-ankenda and M. latifolia were screened for their antimicrobial, antioxidant and cytotoxic activities. Almost all extracts of M. clemensia exhibited moderate growth inhibition when tested against the three pathogenic fungi. However, when tested against pathogenic bacteria, the three leaves extracts showed strong activity against methicillin resistant S. aureus and moderate for the other bacteria. In the antioxidant assay by using DPPH, the three leaves extracts of M. lunu-ankenda exhibited significant activity with with IC50 values of 7.8, 15.6 and 7.8 μg/mL. In addition, the petroleum ether leaves extract of M. clemensiae and the chloroform leaves extract of M. lunu-ankenda showed strong cytotoxic activity when tested against human promyelocytic leukemia (HL60) cell line with IC50 values of 2.8 and 0.8 μg/mL, respectively. Universiti Kebangsaan Malaysia 2009 Article NonPeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/13415/1/Biological%20activities%20of%20four%20Melicope%20species.pdf Mohd Hashim, Najihah and Rahmani, Mawardi and Mohd Ismail, Hazar Bebe and Md. Sukari, Mohd. Aspollah and Ali, Abdul Manaf and Ee, Gwendoline Cheng Lian (2009) Biological activities of four Melicope species. Sains Malaysiana, 38 (5). pp. 767-771. ISSN 0026-6039 |
| spellingShingle | Mohd Hashim, Najihah Rahmani, Mawardi Mohd Ismail, Hazar Bebe Md. Sukari, Mohd. Aspollah Ali, Abdul Manaf Ee, Gwendoline Cheng Lian Biological activities of four Melicope species |
| title | Biological activities of four Melicope species |
| title_full | Biological activities of four Melicope species |
| title_fullStr | Biological activities of four Melicope species |
| title_full_unstemmed | Biological activities of four Melicope species |
| title_short | Biological activities of four Melicope species |
| title_sort | biological activities of four melicope species |
| url | http://psasir.upm.edu.my/id/eprint/13415/1/Biological%20activities%20of%20four%20Melicope%20species.pdf |
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