Brown fat uptake of 18F-FDG on dual time point PET/CT imaging.

The aim of this report was to assess the changes in the 18F-fluorodeoxyglucose (18F-FDG) uptake of brown fats on integrated positron emission tomography/computed tomography (PET/ CT) imaging. The patient presented with an enlargement of the neck lymph nodes, and was suspicious for tuberculous lympha...

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Main Authors: Abdul Razak , Hairil Rashmizal, Abdul Rahim, Noraini, Rossetti, Claudio, Nordin, Abdul Jalil
Format: Article
Language:English
Published: Singapore Medical Association 2010
Online Access:http://psasir.upm.edu.my/id/eprint/13459/1/Brown%20fat%20uptake%20of%2018F.pdf
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author Abdul Razak , Hairil Rashmizal
Abdul Rahim, Noraini
Rossetti, Claudio
Nordin, Abdul Jalil
author_facet Abdul Razak , Hairil Rashmizal
Abdul Rahim, Noraini
Rossetti, Claudio
Nordin, Abdul Jalil
author_sort Abdul Razak , Hairil Rashmizal
collection UPM
description The aim of this report was to assess the changes in the 18F-fluorodeoxyglucose (18F-FDG) uptake of brown fats on integrated positron emission tomography/computed tomography (PET/ CT) imaging. The patient presented with an enlargement of the neck lymph nodes, and was suspicious for tuberculous lymphadenitis. A whole body PET/CT imaging was performed, followed by a delayed imaging of the neck and thoracic regions. A visually increased 18F-FDG uptake was taken as a positive finding. A semi-quantitative evaluation was performed using a maximum standardised uptake value (SUVmax) with a cut-off value above 2.5. There were a number of 18F-FDG avid activity areas seen at the supraclavicular, mediastinal, paravertebral and perirenal regions. These are in keeping with the physiological 18F-FDG uptake in brown fat. The differences in SUVmax between the two scans ranged from -20 percent to +20 percent. Based on our observation, dual time point imaging may not be a reliable method for assessing the 18F-FDG uptake of brown fat.
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spelling upm.eprints-134592015-10-26T06:28:44Z http://psasir.upm.edu.my/id/eprint/13459/ Brown fat uptake of 18F-FDG on dual time point PET/CT imaging. Abdul Razak , Hairil Rashmizal Abdul Rahim, Noraini Rossetti, Claudio Nordin, Abdul Jalil The aim of this report was to assess the changes in the 18F-fluorodeoxyglucose (18F-FDG) uptake of brown fats on integrated positron emission tomography/computed tomography (PET/ CT) imaging. The patient presented with an enlargement of the neck lymph nodes, and was suspicious for tuberculous lymphadenitis. A whole body PET/CT imaging was performed, followed by a delayed imaging of the neck and thoracic regions. A visually increased 18F-FDG uptake was taken as a positive finding. A semi-quantitative evaluation was performed using a maximum standardised uptake value (SUVmax) with a cut-off value above 2.5. There were a number of 18F-FDG avid activity areas seen at the supraclavicular, mediastinal, paravertebral and perirenal regions. These are in keeping with the physiological 18F-FDG uptake in brown fat. The differences in SUVmax between the two scans ranged from -20 percent to +20 percent. Based on our observation, dual time point imaging may not be a reliable method for assessing the 18F-FDG uptake of brown fat. Singapore Medical Association 2010-02 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/13459/1/Brown%20fat%20uptake%20of%2018F.pdf Abdul Razak , Hairil Rashmizal and Abdul Rahim, Noraini and Rossetti, Claudio and Nordin, Abdul Jalil (2010) Brown fat uptake of 18F-FDG on dual time point PET/CT imaging. Singapore Medical Journal, 51 (2). e37-e39. ISSN 0037-5675
spellingShingle Abdul Razak , Hairil Rashmizal
Abdul Rahim, Noraini
Rossetti, Claudio
Nordin, Abdul Jalil
Brown fat uptake of 18F-FDG on dual time point PET/CT imaging.
title Brown fat uptake of 18F-FDG on dual time point PET/CT imaging.
title_full Brown fat uptake of 18F-FDG on dual time point PET/CT imaging.
title_fullStr Brown fat uptake of 18F-FDG on dual time point PET/CT imaging.
title_full_unstemmed Brown fat uptake of 18F-FDG on dual time point PET/CT imaging.
title_short Brown fat uptake of 18F-FDG on dual time point PET/CT imaging.
title_sort brown fat uptake of 18f fdg on dual time point pet ct imaging
url http://psasir.upm.edu.my/id/eprint/13459/1/Brown%20fat%20uptake%20of%2018F.pdf
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