Chemical constituents and antimicrobial activity of Goniothalamus macrophyllus (Annonaceae) from Pasoh Forest Reserve, Malaysia
The essential oils from the twig and root of Goniothalamus macrophyllus were obtained by hydrodistillation and subjected to Gas Chromatography (GC-FID) and Gas Chromatography/Mass Spectrometry (GC-MS) using CBP-5 capillary column in order to determine their chemical composition. Both twig and root o...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Academic Journals
2010
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| Online Access: | http://psasir.upm.edu.my/id/eprint/13568/1/13568.pdf |
| _version_ | 1825945261348749312 |
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| author | Ab Ghani, Siti Humeirah Mohtar, Mastura Mohamad Ali, Nor Azah Jamil, Mailina J. A., Saiful Hamid, Muhajir Abdullah, Mohd Puad |
| author_facet | Ab Ghani, Siti Humeirah Mohtar, Mastura Mohamad Ali, Nor Azah Jamil, Mailina J. A., Saiful Hamid, Muhajir Abdullah, Mohd Puad |
| author_sort | Ab Ghani, Siti Humeirah |
| collection | UPM |
| description | The essential oils from the twig and root of Goniothalamus macrophyllus were obtained by hydrodistillation and subjected to Gas Chromatography (GC-FID) and Gas Chromatography/Mass Spectrometry (GC-MS) using CBP-5 capillary column in order to determine their chemical composition. Both twig and root oils and four reference standard compounds (α-pinene, linalool, geraniol and geranyl acetate) were evaluated for their antimicrobial properties against gram positive and gram negative bacteria, yeast and dermatophyte fungi using broth microdilution methods. The GCMS analysis revealed twenty-one and fourteen compounds from twig and root oils which represented 90.0 and 42.5% of the total oils, respectively. The oils were found to possess the following major components: twig: geranyl acetate (45.5%), geraniol (17.0%), linalool (12.7%) and camphene (7.5%); root: cyperene (9.8%), geranyl acetate (9.4%), geraniol (3.4%) and linalool (2.6%). Other components present in appreciable amounts in both essential oils were α-pinene (0.8%) and benzaldehyde (0.5%). The root oil exhibited the most notable inhibitory activity (0.3 mg/ml) against Vancomycin intermediate-resistance Staphylococcus aureus (VISA 24), Staphylococcus epidermidis and Candida albicans. α-pinene meanwhile inhibited the bacteria and fungal growth at 0.3 and 2.5 mg/ml. With regards to antimicrobial potential, α-pinene superceeds linalool, geraniol and geranyl acetate, respectively. |
| first_indexed | 2024-03-06T07:28:44Z |
| format | Article |
| id | upm.eprints-13568 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T07:28:44Z |
| publishDate | 2010 |
| publisher | Academic Journals |
| record_format | dspace |
| spelling | upm.eprints-135682017-11-09T04:37:14Z http://psasir.upm.edu.my/id/eprint/13568/ Chemical constituents and antimicrobial activity of Goniothalamus macrophyllus (Annonaceae) from Pasoh Forest Reserve, Malaysia Ab Ghani, Siti Humeirah Mohtar, Mastura Mohamad Ali, Nor Azah Jamil, Mailina J. A., Saiful Hamid, Muhajir Abdullah, Mohd Puad The essential oils from the twig and root of Goniothalamus macrophyllus were obtained by hydrodistillation and subjected to Gas Chromatography (GC-FID) and Gas Chromatography/Mass Spectrometry (GC-MS) using CBP-5 capillary column in order to determine their chemical composition. Both twig and root oils and four reference standard compounds (α-pinene, linalool, geraniol and geranyl acetate) were evaluated for their antimicrobial properties against gram positive and gram negative bacteria, yeast and dermatophyte fungi using broth microdilution methods. The GCMS analysis revealed twenty-one and fourteen compounds from twig and root oils which represented 90.0 and 42.5% of the total oils, respectively. The oils were found to possess the following major components: twig: geranyl acetate (45.5%), geraniol (17.0%), linalool (12.7%) and camphene (7.5%); root: cyperene (9.8%), geranyl acetate (9.4%), geraniol (3.4%) and linalool (2.6%). Other components present in appreciable amounts in both essential oils were α-pinene (0.8%) and benzaldehyde (0.5%). The root oil exhibited the most notable inhibitory activity (0.3 mg/ml) against Vancomycin intermediate-resistance Staphylococcus aureus (VISA 24), Staphylococcus epidermidis and Candida albicans. α-pinene meanwhile inhibited the bacteria and fungal growth at 0.3 and 2.5 mg/ml. With regards to antimicrobial potential, α-pinene superceeds linalool, geraniol and geranyl acetate, respectively. Academic Journals 2010 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/13568/1/13568.pdf Ab Ghani, Siti Humeirah and Mohtar, Mastura and Mohamad Ali, Nor Azah and Jamil, Mailina and J. A., Saiful and Hamid, Muhajir and Abdullah, Mohd Puad (2010) Chemical constituents and antimicrobial activity of Goniothalamus macrophyllus (Annonaceae) from Pasoh Forest Reserve, Malaysia. African Journal of Biotechnology, 9 (34). art. no. 69CB0E332566. pp. 5511-5515. ISSN 1684–5315 http://www.academicjournals.org/journal/AJB/article-abstract/69CB0E332566 |
| spellingShingle | Ab Ghani, Siti Humeirah Mohtar, Mastura Mohamad Ali, Nor Azah Jamil, Mailina J. A., Saiful Hamid, Muhajir Abdullah, Mohd Puad Chemical constituents and antimicrobial activity of Goniothalamus macrophyllus (Annonaceae) from Pasoh Forest Reserve, Malaysia |
| title | Chemical constituents and antimicrobial activity of Goniothalamus macrophyllus (Annonaceae) from Pasoh Forest Reserve, Malaysia |
| title_full | Chemical constituents and antimicrobial activity of Goniothalamus macrophyllus (Annonaceae) from Pasoh Forest Reserve, Malaysia |
| title_fullStr | Chemical constituents and antimicrobial activity of Goniothalamus macrophyllus (Annonaceae) from Pasoh Forest Reserve, Malaysia |
| title_full_unstemmed | Chemical constituents and antimicrobial activity of Goniothalamus macrophyllus (Annonaceae) from Pasoh Forest Reserve, Malaysia |
| title_short | Chemical constituents and antimicrobial activity of Goniothalamus macrophyllus (Annonaceae) from Pasoh Forest Reserve, Malaysia |
| title_sort | chemical constituents and antimicrobial activity of goniothalamus macrophyllus annonaceae from pasoh forest reserve malaysia |
| url | http://psasir.upm.edu.my/id/eprint/13568/1/13568.pdf |
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