Cis-clerodane-type furanoditerpenoids from Tinospora crispa
Phytochemical and cytotoxicity investigations on organic solvent extracts of the aerial parts of Tinospora crispa have led to the isolation of 15 cis-clerodane-type furanoditerpenoids. Of these, nine compounds (1-9) were found to be new. Spectroscopic assignments of a previously reported compound, b...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society
2010
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| Online Access: | http://psasir.upm.edu.my/id/eprint/13597/1/Cis-clerodane-type%20furanoditerpenoids%20from%20Tinospora%20crispa.pdf |
| Summary: | Phytochemical and cytotoxicity investigations on organic solvent extracts of the aerial parts of Tinospora crispa have led to the isolation of 15 cis-clerodane-type furanoditerpenoids. Of these, nine compounds (1-9) were found to be new. Spectroscopic assignments of a previously reported compound, borapetoside A (13), were revised on the basis of HMQC and HMBC correlations. No discernible activity was observed when compounds 10-13 were subjected to evaluation in cytotoxicity assays against human prostate cancer (PC-3) and the normal mouse fibroblast (3T3) cell lines. |
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