GEE-smoothing spline for semiparametric estimation of longitudinal binary data

This paper considers analyzing longitudinal data semiparametrically and proposing GEE-Smoothing spline in the estimation of the parametric and nonparametric components. Generalized estimating equation is used as the core of the estimation. Estimation of association or within subject correlation used...

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Main Authors: Suliadi, Ibrahim, Noor Akma, Daud, Isa, Krishnarajah, Isthrinayagy S.
Format: Article
Published: Centre for Environment, Social and Economic Research Publications 2010
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author Suliadi,
Ibrahim, Noor Akma
Daud, Isa
Krishnarajah, Isthrinayagy S.
author_facet Suliadi,
Ibrahim, Noor Akma
Daud, Isa
Krishnarajah, Isthrinayagy S.
author_sort Suliadi,
collection UPM
description This paper considers analyzing longitudinal data semiparametrically and proposing GEE-Smoothing spline in the estimation of the parametric and nonparametric components. Generalized estimating equation is used as the core of the estimation. Estimation of association or within subject correlation used method of moment suggested by Liang and Zeger (1986). In the estimation of nonparametric component, we used smoothing spline approach specifically the natural cubic spline. We show through simulation that GEE-Smoothing Spline has good properties. The bias of parametric and nonparametric estimators decrease with increasing sample size. These estimators are also consistent even though incorrect correlation structure is used. The most efficient estimator can be obtained if the correct correlation structure is used rather than ignore the dependency.
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institution Universiti Putra Malaysia
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spelling upm.eprints-148542015-07-31T06:49:40Z http://psasir.upm.edu.my/id/eprint/14854/ GEE-smoothing spline for semiparametric estimation of longitudinal binary data Suliadi, Ibrahim, Noor Akma Daud, Isa Krishnarajah, Isthrinayagy S. This paper considers analyzing longitudinal data semiparametrically and proposing GEE-Smoothing spline in the estimation of the parametric and nonparametric components. Generalized estimating equation is used as the core of the estimation. Estimation of association or within subject correlation used method of moment suggested by Liang and Zeger (1986). In the estimation of nonparametric component, we used smoothing spline approach specifically the natural cubic spline. We show through simulation that GEE-Smoothing Spline has good properties. The bias of parametric and nonparametric estimators decrease with increasing sample size. These estimators are also consistent even though incorrect correlation structure is used. The most efficient estimator can be obtained if the correct correlation structure is used rather than ignore the dependency. Centre for Environment, Social and Economic Research Publications 2010 Article PeerReviewed Suliadi, and Ibrahim, Noor Akma and Daud, Isa and Krishnarajah, Isthrinayagy S. (2010) GEE-smoothing spline for semiparametric estimation of longitudinal binary data. International Journal of Applied Mathematics and Statistics, 18 (S10). pp. 82-95. ISSN 0973-1377; ESSN: 0973-7545 http://www.ceser.in/ceserp/index.php/ijamas/article/view/573
spellingShingle Suliadi,
Ibrahim, Noor Akma
Daud, Isa
Krishnarajah, Isthrinayagy S.
GEE-smoothing spline for semiparametric estimation of longitudinal binary data
title GEE-smoothing spline for semiparametric estimation of longitudinal binary data
title_full GEE-smoothing spline for semiparametric estimation of longitudinal binary data
title_fullStr GEE-smoothing spline for semiparametric estimation of longitudinal binary data
title_full_unstemmed GEE-smoothing spline for semiparametric estimation of longitudinal binary data
title_short GEE-smoothing spline for semiparametric estimation of longitudinal binary data
title_sort gee smoothing spline for semiparametric estimation of longitudinal binary data
work_keys_str_mv AT suliadi geesmoothingsplineforsemiparametricestimationoflongitudinalbinarydata
AT ibrahimnoorakma geesmoothingsplineforsemiparametricestimationoflongitudinalbinarydata
AT daudisa geesmoothingsplineforsemiparametricestimationoflongitudinalbinarydata
AT krishnarajahisthrinayagys geesmoothingsplineforsemiparametricestimationoflongitudinalbinarydata