Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome

Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome

Background: Down syndrome (DS) individuals suffer mental retardation with further cognitive decline and early onset Alzheimer's disease. Methodology/Principal Findings: To understand how trisomy 21 causes these neurological abnormalities we investigated changes in gene expression networ...

Full description

Bibliographic Details
Main Authors: Hewitt, Chelsee Ann, Ling, King Hwa, Merson, Tobias D., Simpson, Ken M., Ritchie, Matthew E., King, Sarah L., Pritchard, Melanie A., Smyth, Gordon K., Thomas, Tim, Scott, Hamish S., Voss, Anne K.
Format: Article
Language:English
Published: Public Library of Science 2010
Online Access:http://psasir.upm.edu.my/id/eprint/14865/1/14865.PDF

Similar Items

Similar Items