Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome
Background: Down syndrome (DS) individuals suffer mental retardation with further cognitive decline and early onset Alzheimer's disease. Methodology/Principal Findings: To understand how trisomy 21 causes these neurological abnormalities we investigated changes in gene expression networ...
Main Authors: | Hewitt, Chelsee Ann, Ling, King Hwa, Merson, Tobias D., Simpson, Ken M., Ritchie, Matthew E., King, Sarah L., Pritchard, Melanie A., Smyth, Gordon K., Thomas, Tim, Scott, Hamish S., Voss, Anne K. |
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格式: | 文件 |
语言: | English |
出版: |
Public Library of Science
2010
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在线阅读: | http://psasir.upm.edu.my/id/eprint/14865/1/14865.PDF |
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