Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome

Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome

Background: Down syndrome (DS) individuals suffer mental retardation with further cognitive decline and early onset Alzheimer's disease. Methodology/Principal Findings: To understand how trisomy 21 causes these neurological abnormalities we investigated changes in gene expression networ...

Полное описание

Библиографические подробности
Главные авторы:	Hewitt, Chelsee Ann, Ling, King Hwa, Merson, Tobias D., Simpson, Ken M., Ritchie, Matthew E., King, Sarah L., Pritchard, Melanie A., Smyth, Gordon K., Thomas, Tim, Scott, Hamish S., Voss, Anne K.
Формат:	Статья
Язык:	English
Опубликовано:	Public Library of Science 2010
Online-ссылка:	http://psasir.upm.edu.my/id/eprint/14865/1/14865.PDF

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