Green synthesis of lauryl palmitate via lipase-catalyzed reaction
Enzyme catalysis is most attractive for the synthesis of fine organic compounds, which are difficult to prepare and to handle by conventional means. In this work, green synthesis of lauryl palmitate, a wax ester was successfully carried out by lipase-catalyzed esterification of palmitic acid and lau...
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| Format: | Article |
| Language: | English |
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IDOSI Publications
2010
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| Online Access: | http://psasir.upm.edu.my/id/eprint/14915/1/Green%20synthesis%20of%20lauryl%20palmitate%20via%20lipase.pdf |
| _version_ | 1825945520284106752 |
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| author | Muhamad @ Wahab, Syamsul Kamar Mat Radzi, Salina Othman, Siti Salhah Mohd Noor, Hanina Abdul Rahman, Mohd Basyaruddin Jusoff, Kamaruzaman |
| author_facet | Muhamad @ Wahab, Syamsul Kamar Mat Radzi, Salina Othman, Siti Salhah Mohd Noor, Hanina Abdul Rahman, Mohd Basyaruddin Jusoff, Kamaruzaman |
| author_sort | Muhamad @ Wahab, Syamsul Kamar |
| collection | UPM |
| description | Enzyme catalysis is most attractive for the synthesis of fine organic compounds, which are difficult to prepare and to handle by conventional means. In this work, green synthesis of lauryl palmitate, a wax ester was successfully carried out by lipase-catalyzed esterification of palmitic acid and lauryl alcohol. In this study, commercial immobilized lipase from Candida antartica (Novozym 435) was used as biocatalyst. The effect of various reaction parameters were optimized to obtain a high yield of wax esters. The optimum condition to produce lauryl palmitate was at reaction time (RT); 10 min, temperature (T); 40°C, amount of enzyme (E); 0.4 g, molar ratio of substrate (N); 2:1 and organic solvents of log P>3.5. The product was then subjected to characterize using Fourier-transform infrared spectroscopy (FT-IR) and Gas chromatography spectroscopy (GC) to ensure the purity of product obtained. Analysis of yield showed that at optimum condition, lauryl palmitate was produced in short time with high purity, >90%. |
| first_indexed | 2024-03-06T07:32:48Z |
| format | Article |
| id | upm.eprints-14915 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T07:32:48Z |
| publishDate | 2010 |
| publisher | IDOSI Publications |
| record_format | dspace |
| spelling | upm.eprints-149152020-06-16T07:05:32Z http://psasir.upm.edu.my/id/eprint/14915/ Green synthesis of lauryl palmitate via lipase-catalyzed reaction Muhamad @ Wahab, Syamsul Kamar Mat Radzi, Salina Othman, Siti Salhah Mohd Noor, Hanina Abdul Rahman, Mohd Basyaruddin Jusoff, Kamaruzaman Enzyme catalysis is most attractive for the synthesis of fine organic compounds, which are difficult to prepare and to handle by conventional means. In this work, green synthesis of lauryl palmitate, a wax ester was successfully carried out by lipase-catalyzed esterification of palmitic acid and lauryl alcohol. In this study, commercial immobilized lipase from Candida antartica (Novozym 435) was used as biocatalyst. The effect of various reaction parameters were optimized to obtain a high yield of wax esters. The optimum condition to produce lauryl palmitate was at reaction time (RT); 10 min, temperature (T); 40°C, amount of enzyme (E); 0.4 g, molar ratio of substrate (N); 2:1 and organic solvents of log P>3.5. The product was then subjected to characterize using Fourier-transform infrared spectroscopy (FT-IR) and Gas chromatography spectroscopy (GC) to ensure the purity of product obtained. Analysis of yield showed that at optimum condition, lauryl palmitate was produced in short time with high purity, >90%. IDOSI Publications 2010 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/14915/1/Green%20synthesis%20of%20lauryl%20palmitate%20via%20lipase.pdf Muhamad @ Wahab, Syamsul Kamar and Mat Radzi, Salina and Othman, Siti Salhah and Mohd Noor, Hanina and Abdul Rahman, Mohd Basyaruddin and Jusoff, Kamaruzaman (2010) Green synthesis of lauryl palmitate via lipase-catalyzed reaction. World Applied Sciences Journal, 11 (4). pp. 401-407. ISSN 1818-4952; ESSN: 1991-6426 https://www.idosi.org/wasj/wasj11(4)2010.htm |
| spellingShingle | Muhamad @ Wahab, Syamsul Kamar Mat Radzi, Salina Othman, Siti Salhah Mohd Noor, Hanina Abdul Rahman, Mohd Basyaruddin Jusoff, Kamaruzaman Green synthesis of lauryl palmitate via lipase-catalyzed reaction |
| title | Green synthesis of lauryl palmitate via lipase-catalyzed reaction |
| title_full | Green synthesis of lauryl palmitate via lipase-catalyzed reaction |
| title_fullStr | Green synthesis of lauryl palmitate via lipase-catalyzed reaction |
| title_full_unstemmed | Green synthesis of lauryl palmitate via lipase-catalyzed reaction |
| title_short | Green synthesis of lauryl palmitate via lipase-catalyzed reaction |
| title_sort | green synthesis of lauryl palmitate via lipase catalyzed reaction |
| url | http://psasir.upm.edu.my/id/eprint/14915/1/Green%20synthesis%20of%20lauryl%20palmitate%20via%20lipase.pdf |
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