Naturally occurring labdane diterpene and benzofuran from Globba pendula.
Phytochemical investigation on Globba pendula resulted in the isolation of a new naturally occurring 16-oxo-(8)17-12-labdadien-15,11-olide 1 and benzofuran-2-carboxaldehyde 2. Other known compounds including isoandrographolide, indirubin, vanillin, vanillic acid, 2(3H)-benzoxazolone, as well as beta...
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| Format: | Article |
| Language: | English |
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Natural Product Communications
2009
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| _version_ | 1825945688425365504 |
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| author | Maulidiani, H.M Shaari , Khozirah Paetz , ChristiaN Stanslas, Johnson Abas, Faridah Lajis, Nordin |
| author_facet | Maulidiani, H.M Shaari , Khozirah Paetz , ChristiaN Stanslas, Johnson Abas, Faridah Lajis, Nordin |
| author_sort | Maulidiani, H.M |
| collection | UPM |
| description | Phytochemical investigation on Globba pendula resulted in the isolation of a new naturally occurring 16-oxo-(8)17-12-labdadien-15,11-olide 1 and benzofuran-2-carboxaldehyde 2. Other known compounds including isoandrographolide, indirubin, vanillin, vanillic acid, 2(3H)-benzoxazolone, as well as beta-sitosteryl-beta-D-glucopyranoside, beta-sitosterol, and 7alpha-hydroxysitosterol were also isolated. The structures were established based on spectroscopic data and comparison with the literature. Furthermore, the compound isoandrographolide has demonstrated strong cytotoxic properties towards a panel of cancer cell lines (MCF-7, PC-3, and H-460) with the IC50 values of 7.9, 8.7, and 9.0 microM, respectively. |
| first_indexed | 2024-03-06T07:35:22Z |
| format | Article |
| id | upm.eprints-15783 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T07:35:22Z |
| publishDate | 2009 |
| publisher | Natural Product Communications |
| record_format | dspace |
| spelling | upm.eprints-157832013-05-22T03:21:14Z http://psasir.upm.edu.my/id/eprint/15783/ Naturally occurring labdane diterpene and benzofuran from Globba pendula. Maulidiani, H.M Shaari , Khozirah Paetz , ChristiaN Stanslas, Johnson Abas, Faridah Lajis, Nordin Phytochemical investigation on Globba pendula resulted in the isolation of a new naturally occurring 16-oxo-(8)17-12-labdadien-15,11-olide 1 and benzofuran-2-carboxaldehyde 2. Other known compounds including isoandrographolide, indirubin, vanillin, vanillic acid, 2(3H)-benzoxazolone, as well as beta-sitosteryl-beta-D-glucopyranoside, beta-sitosterol, and 7alpha-hydroxysitosterol were also isolated. The structures were established based on spectroscopic data and comparison with the literature. Furthermore, the compound isoandrographolide has demonstrated strong cytotoxic properties towards a panel of cancer cell lines (MCF-7, PC-3, and H-460) with the IC50 values of 7.9, 8.7, and 9.0 microM, respectively. Natural Product Communications 2009 Article PeerReviewed Maulidiani, H.M and Shaari , Khozirah and Paetz , ChristiaN and Stanslas, Johnson and Abas, Faridah and Lajis, Nordin (2009) Naturally occurring labdane diterpene and benzofuran from Globba pendula. Natural Product Communications, 4 (8). pp. 1031-1036. ISSN 1934-578X English |
| spellingShingle | Maulidiani, H.M Shaari , Khozirah Paetz , ChristiaN Stanslas, Johnson Abas, Faridah Lajis, Nordin Naturally occurring labdane diterpene and benzofuran from Globba pendula. |
| title | Naturally occurring labdane diterpene and benzofuran from Globba pendula. |
| title_full | Naturally occurring labdane diterpene and benzofuran from Globba pendula. |
| title_fullStr | Naturally occurring labdane diterpene and benzofuran from Globba pendula. |
| title_full_unstemmed | Naturally occurring labdane diterpene and benzofuran from Globba pendula. |
| title_short | Naturally occurring labdane diterpene and benzofuran from Globba pendula. |
| title_sort | naturally occurring labdane diterpene and benzofuran from globba pendula |
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