Defects in nerve conduction velocity and different muscle fibre-type specificity contribute to muscle weakness in Ts1Cje Down syndrome mouse model

Background: Down syndrome (DS) is a genetic disorder caused by presence of extra copy of human chromosome 21. It is characterised by several clinical phenotypes. Motor dysfunction due to hypotonia is commonly seen in individuals with DS and its etiology is yet unknown. Ts1Cje, which has a partial tr...

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Detalhes bibliográficos
Principais autores: Bala, Usman, Leong, Melody Pui Yee, Lim, Chai Ling, Kadir @ Shahar, Hayati, Othman, Fauziah, Lai, Mei I., Law, Zhe Kang, Ramli, Khairunnisa, Htwe, Ohnmar, Ling, King Hwa, Cheah, Pike See
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science 2018
Acesso em linha:http://psasir.upm.edu.my/id/eprint/15954/1/15954.pdf

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