Selection of high affinity ligands to hepatitis B core antigen from a phage-displayed cyclic peptide library.
M13 phages that display random disulfide constrained heptapeptides on their gpIII proteins were used to select for high affinity ligands to hepatitis B core antigen (HBcAg). Phages bearing the amino acid sequences C-WSFFSNI-C and C-WPFWGPW-C were isolated, and a binding assay in solution showed that...
Main Authors: | Ho, Kok Lian, Yusoff, Khatijah, Seow, Heng Fong, Tan, Wen Siang |
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Format: | Article |
Language: | English English English |
Published: |
Wiley-blackwell
2003
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Subjects: | |
Online Access: | http://psasir.upm.edu.my/id/eprint/16650/1/Selection%20of%20high%20affinity%20ligands%20to%20hepatitis%20B%20core%20antigen%20from%20a%20phage.pdf http://psasir.upm.edu.my/id/eprint/16650/7/Journal%20of%20Medical%20Virology%20-%202002%20-%20Ho%20-%20Selection%20of%20high%20affinity%20ligands%20to%20hepatitis%20B%20core%20antigen%20from%20a.pdf |
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