Silver/poly (lactic acid) nanocomposites: preparation, characterization, and antibacterial activity
In this study, antibacterial characteristic of silver/poly (lactic acid) nanocomposite (Ag/PLA-NC) films was investigated, while silver nanoparticles (Ag-NPs) were synthesized into biodegradable PLA via chemical reduction method in diphase solvent. Silver nitrate and sodium borohydride were respecti...
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| Format: | Article |
| Language: | English |
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Dove Medical Press Ltd.
2010
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| author | Shameli, Kamyar Ahmad, Mansor Wan Yunus, Wan Md. Zin Ibrahim, Nor Azowa Abdul Rahman, Russly Jokar, Maryam Darroudi, Majid |
| author_facet | Shameli, Kamyar Ahmad, Mansor Wan Yunus, Wan Md. Zin Ibrahim, Nor Azowa Abdul Rahman, Russly Jokar, Maryam Darroudi, Majid |
| author_sort | Shameli, Kamyar |
| collection | UPM |
| description | In this study, antibacterial characteristic of silver/poly (lactic acid) nanocomposite (Ag/PLA-NC) films was investigated, while silver nanoparticles (Ag-NPs) were synthesized into biodegradable PLA via chemical reduction method in diphase solvent. Silver nitrate and sodium borohydride were respectively used as a silver precursor and reducing agent in the PLA, which acted as a polymeric matrix and stabilizer. Meanwhile, the properties of
Ag/PLA-NCs were studied as a function of the Ag-NP weight percentages (8, 16, and 32 wt% respectively), in relation to the use of PLA. The morphology of the Ag/PLA-NC films and
the distribution of the Ag-NPs were also characterized. The silver ions released from the Ag/PLA-NC films and their antibacterial activities were scrutinized. The antibacterial activities of the Ag/PLA-NC films were examined against Gram-negative bacteria (Escherichia
coli and Vibrio parahaemolyticus) and Gram-positive bacteria (Staphylococcus aureus) by diffusion method using Muller–Hinton agar. The results indicated that Ag/PLA-NC films possessed a strong antibacterial activity with the increase in the percentage of Ag-NPs in the PLA. Thus, Ag/PLA-NC films can be used as an antibacterial scaffold for tissue engineering and medical application. |
| first_indexed | 2024-03-06T07:38:13Z |
| format | Article |
| id | upm.eprints-16710 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T07:38:13Z |
| publishDate | 2010 |
| publisher | Dove Medical Press Ltd. |
| record_format | dspace |
| spelling | upm.eprints-167102013-01-29T10:11:53Z http://psasir.upm.edu.my/id/eprint/16710/ Silver/poly (lactic acid) nanocomposites: preparation, characterization, and antibacterial activity Shameli, Kamyar Ahmad, Mansor Wan Yunus, Wan Md. Zin Ibrahim, Nor Azowa Abdul Rahman, Russly Jokar, Maryam Darroudi, Majid In this study, antibacterial characteristic of silver/poly (lactic acid) nanocomposite (Ag/PLA-NC) films was investigated, while silver nanoparticles (Ag-NPs) were synthesized into biodegradable PLA via chemical reduction method in diphase solvent. Silver nitrate and sodium borohydride were respectively used as a silver precursor and reducing agent in the PLA, which acted as a polymeric matrix and stabilizer. Meanwhile, the properties of Ag/PLA-NCs were studied as a function of the Ag-NP weight percentages (8, 16, and 32 wt% respectively), in relation to the use of PLA. The morphology of the Ag/PLA-NC films and the distribution of the Ag-NPs were also characterized. The silver ions released from the Ag/PLA-NC films and their antibacterial activities were scrutinized. The antibacterial activities of the Ag/PLA-NC films were examined against Gram-negative bacteria (Escherichia coli and Vibrio parahaemolyticus) and Gram-positive bacteria (Staphylococcus aureus) by diffusion method using Muller–Hinton agar. The results indicated that Ag/PLA-NC films possessed a strong antibacterial activity with the increase in the percentage of Ag-NPs in the PLA. Thus, Ag/PLA-NC films can be used as an antibacterial scaffold for tissue engineering and medical application. Dove Medical Press Ltd. 2010-08 Article PeerReviewed Shameli, Kamyar and Ahmad, Mansor and Wan Yunus, Wan Md. Zin and Ibrahim, Nor Azowa and Abdul Rahman, Russly and Jokar, Maryam and Darroudi, Majid (2010) Silver/poly (lactic acid) nanocomposites: preparation, characterization, and antibacterial activity. International Journal of Nanomedicine, 5. pp. 573-579. ISSN 1176-9114 Nanocomposites (Materials) Nanoparticles Antibacterial agents 10.2147/IJN.S12007 English |
| spellingShingle | Nanocomposites (Materials) Nanoparticles Antibacterial agents Shameli, Kamyar Ahmad, Mansor Wan Yunus, Wan Md. Zin Ibrahim, Nor Azowa Abdul Rahman, Russly Jokar, Maryam Darroudi, Majid Silver/poly (lactic acid) nanocomposites: preparation, characterization, and antibacterial activity |
| title | Silver/poly (lactic acid) nanocomposites: preparation, characterization, and antibacterial activity |
| title_full | Silver/poly (lactic acid) nanocomposites: preparation, characterization, and antibacterial activity |
| title_fullStr | Silver/poly (lactic acid) nanocomposites: preparation, characterization, and antibacterial activity |
| title_full_unstemmed | Silver/poly (lactic acid) nanocomposites: preparation, characterization, and antibacterial activity |
| title_short | Silver/poly (lactic acid) nanocomposites: preparation, characterization, and antibacterial activity |
| title_sort | silver poly lactic acid nanocomposites preparation characterization and antibacterial activity |
| topic | Nanocomposites (Materials) Nanoparticles Antibacterial agents |
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