Structure of a glycosylphosphatidylinositol-anchored domain from a trypanosome variant surface glycoprotein.
The cell surface of African trypanosomes is covered by a densely packed monolayer of a single protein, the variant surface glycoprotein (VSG). The VSG protects the trypanosome cell surface from effector molecules of the host immune system and is the mediator of antigenic variation. The sequence dive...
Main Authors: | Jones, Nicola G., Nietlispach, Daniel, Kumar Sharma, Reuben Sunil, Burke, David F., Eyres, Isobel, Mues, Marsilius, Mott, Helen R., Carrington, Mark |
---|---|
Format: | Article |
Language: | English English |
Published: |
American Society for Biochemistry and Molecular Biology
2008
|
Online Access: | http://psasir.upm.edu.my/id/eprint/16872/1/Structure%20of%20a%20glycosylphosphatidylinositol.pdf |
Similar Items
-
Asymmetric cell division as a route to reduction in cell length and change in cell morphology in trypanosomes.
by: Kumar Sharma, Reuben Sunil, et al.
Published: (2008) -
Antitrypanosomal and cytotoxic activities of selected medicinal plants and effect of Cordyline terminalis on trypanosomal nuclear and kinetoplast replication
by: Dyary, Hiewa O., et al.
Published: (2014) -
Chemical Genomics-Based Antifungal Drug Discovery: Targeting Glycosylphosphatidylinositol (GPI) Precursor Biosynthesis
by: Mann, Paul A., et al.
Published: (2016) -
Epidemiology of Trypanosoma evansi infection in horses in Peninsular Malaysia and the variant surface glycoprotein of the isolates
by: Elshafie, Elshafie Ibrahim
Published: (2011) -
Identification of Trypanosome Proteins in Plasma from African Sleeping Sickness Patients Infected with T. b. rhodesiense
by: Eyford, Brett A., et al.
Published: (2013)