Relationship between exposure to particulate matter and biomarkers among bus drivers in Klang Valley, Malaysia
This cross-sectional comparative study investigates the association between particulate matters (PM; PM10, PM2.5 and ultrafine particle (UFP) and concentration of biomarkers; Interleukin-6 (IL-6) and Tumor Necrosis Factor-Alpha (TNF-α) using 62 bus drivers as exposed group and 62 administrative staf...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
School of Health Sciences, Universiti Sains Malaysia
2011
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/17307/1/Relationship%20between%20exposure%20to%20particulate%20matter%20and%20biomarkers%20among%20bus%20drivers%20in%20Klang%20Valley%2C%20Malaysia.pdf |
| _version_ | 1796969229821411328 |
|---|---|
| author | M., Kavitha Jalaludin, Juliana Md. Akim, Abdah |
| author_facet | M., Kavitha Jalaludin, Juliana Md. Akim, Abdah |
| author_sort | M., Kavitha |
| collection | UPM |
| description | This cross-sectional comparative study investigates the association between particulate matters (PM; PM10, PM2.5 and ultrafine particle (UFP) and concentration of biomarkers; Interleukin-6 (IL-6) and Tumor Necrosis Factor-Alpha (TNF-α) using 62 bus drivers as exposed group and 62 administrative staff as comparative group in Klang Valley, Malaysia. T-test results showed that the mean exposure level of PM10 (t = 8.14, p<0.01), PM2.5 (t = 9.95, p<0.01) and UFP (t = 19.61, p<0.01) were significantly higher among the bus drivers compared to comparative group. Mann-Whitney U test of IL-6 (z = -2.43, p<0.05) and TNF-α (z = -5.88, p<0.01) were also found to be significantly higher in the bus drivers. Positive correlations were found between the exposure level of PM and concentration of biomarkers. In conclusion, the bus drivers showed higher concentration of IL-6 and TNF-α and were at a higher risk of getting respiratory illnesses compared to comparative group. Thus, more attention should be e given on the control of high level of exposure to PM in order to minimize the adverse health effects among the groups at risk. |
| first_indexed | 2024-03-06T07:40:02Z |
| format | Article |
| id | upm.eprints-17307 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T07:40:02Z |
| publishDate | 2011 |
| publisher | School of Health Sciences, Universiti Sains Malaysia |
| record_format | dspace |
| spelling | upm.eprints-173072016-04-08T07:58:00Z http://psasir.upm.edu.my/id/eprint/17307/ Relationship between exposure to particulate matter and biomarkers among bus drivers in Klang Valley, Malaysia M., Kavitha Jalaludin, Juliana Md. Akim, Abdah This cross-sectional comparative study investigates the association between particulate matters (PM; PM10, PM2.5 and ultrafine particle (UFP) and concentration of biomarkers; Interleukin-6 (IL-6) and Tumor Necrosis Factor-Alpha (TNF-α) using 62 bus drivers as exposed group and 62 administrative staff as comparative group in Klang Valley, Malaysia. T-test results showed that the mean exposure level of PM10 (t = 8.14, p<0.01), PM2.5 (t = 9.95, p<0.01) and UFP (t = 19.61, p<0.01) were significantly higher among the bus drivers compared to comparative group. Mann-Whitney U test of IL-6 (z = -2.43, p<0.05) and TNF-α (z = -5.88, p<0.01) were also found to be significantly higher in the bus drivers. Positive correlations were found between the exposure level of PM and concentration of biomarkers. In conclusion, the bus drivers showed higher concentration of IL-6 and TNF-α and were at a higher risk of getting respiratory illnesses compared to comparative group. Thus, more attention should be e given on the control of high level of exposure to PM in order to minimize the adverse health effects among the groups at risk. School of Health Sciences, Universiti Sains Malaysia 2011-05-31 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/17307/1/Relationship%20between%20exposure%20to%20particulate%20matter%20and%20biomarkers%20among%20bus%20drivers%20in%20Klang%20Valley%2C%20Malaysia.pdf M., Kavitha and Jalaludin, Juliana and Md. Akim, Abdah (2011) Relationship between exposure to particulate matter and biomarkers among bus drivers in Klang Valley, Malaysia. Health and the Environment Journal, 2 (2). pp. 1-7. ISSN 180-1126 http://www.hej.kk.usm.my/volume2no2.php |
| spellingShingle | M., Kavitha Jalaludin, Juliana Md. Akim, Abdah Relationship between exposure to particulate matter and biomarkers among bus drivers in Klang Valley, Malaysia |
| title | Relationship between exposure to particulate matter and biomarkers among bus drivers in Klang Valley, Malaysia |
| title_full | Relationship between exposure to particulate matter and biomarkers among bus drivers in Klang Valley, Malaysia |
| title_fullStr | Relationship between exposure to particulate matter and biomarkers among bus drivers in Klang Valley, Malaysia |
| title_full_unstemmed | Relationship between exposure to particulate matter and biomarkers among bus drivers in Klang Valley, Malaysia |
| title_short | Relationship between exposure to particulate matter and biomarkers among bus drivers in Klang Valley, Malaysia |
| title_sort | relationship between exposure to particulate matter and biomarkers among bus drivers in klang valley malaysia |
| url | http://psasir.upm.edu.my/id/eprint/17307/1/Relationship%20between%20exposure%20to%20particulate%20matter%20and%20biomarkers%20among%20bus%20drivers%20in%20Klang%20Valley%2C%20Malaysia.pdf |
| work_keys_str_mv | AT mkavitha relationshipbetweenexposuretoparticulatematterandbiomarkersamongbusdriversinklangvalleymalaysia AT jalaludinjuliana relationshipbetweenexposuretoparticulatematterandbiomarkersamongbusdriversinklangvalleymalaysia AT mdakimabdah relationshipbetweenexposuretoparticulatematterandbiomarkersamongbusdriversinklangvalleymalaysia |