Development of Bioaffinity Chromatography for Uricase Purification

The uricase inhibitors urate, xanthine, oxonate and cyanurate were tried as ligands, for preparing bioaffinity support for chromatographic separation of uricase. Only derivatised purines showed inhibitory properties, whereas derivatised s-triazines seemed to lose their absorptive capacity. Chromatog...

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Main Author: Salleh, Abu Bakar
Format: Article
Language:English
English
Published: 1980
Online Access:http://psasir.upm.edu.my/id/eprint/2056/1/Development_of_Bioaffinity_Chromatography_for.pdf
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author Salleh, Abu Bakar
author_facet Salleh, Abu Bakar
author_sort Salleh, Abu Bakar
collection UPM
description The uricase inhibitors urate, xanthine, oxonate and cyanurate were tried as ligands, for preparing bioaffinity support for chromatographic separation of uricase. Only derivatised purines showed inhibitory properties, whereas derivatised s-triazines seemed to lose their absorptive capacity. Chromatographic separation on a bioaffinity support produced higher yield and better purification of Uricase than conventional chromatographic technique.
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spelling upm.eprints-20562013-05-27T06:58:31Z http://psasir.upm.edu.my/id/eprint/2056/ Development of Bioaffinity Chromatography for Uricase Purification Salleh, Abu Bakar The uricase inhibitors urate, xanthine, oxonate and cyanurate were tried as ligands, for preparing bioaffinity support for chromatographic separation of uricase. Only derivatised purines showed inhibitory properties, whereas derivatised s-triazines seemed to lose their absorptive capacity. Chromatographic separation on a bioaffinity support produced higher yield and better purification of Uricase than conventional chromatographic technique. 1980 Article NonPeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/2056/1/Development_of_Bioaffinity_Chromatography_for.pdf Salleh, Abu Bakar (1980) Development of Bioaffinity Chromatography for Uricase Purification. Pertanika, 3 (2). pp. 97-102. English
spellingShingle Salleh, Abu Bakar
Development of Bioaffinity Chromatography for Uricase Purification
title Development of Bioaffinity Chromatography for Uricase Purification
title_full Development of Bioaffinity Chromatography for Uricase Purification
title_fullStr Development of Bioaffinity Chromatography for Uricase Purification
title_full_unstemmed Development of Bioaffinity Chromatography for Uricase Purification
title_short Development of Bioaffinity Chromatography for Uricase Purification
title_sort development of bioaffinity chromatography for uricase purification
url http://psasir.upm.edu.my/id/eprint/2056/1/Development_of_Bioaffinity_Chromatography_for.pdf
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