Antioxidant, anti-inflammatory and anticancer activities of methanolic extracts from Jatropha curcas Linn.
A comprehensive study on the phytochemical contents and biological activities of the methanolic extract from different parts of Jatropha curcas Linn. was conducted. The extracts of different plant parts contained various levels of phenolics, flavonoids and saponins. Latex and leaf extracts showed th...
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| Format: | Article |
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Academic Journals
2011
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| _version_ | 1796970140820045824 |
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| author | Oskoueian, Ehsan Abdullah, Norhani Saad, Wan Zuhainis Omar, Abdul Rahman Ahmad, Syahida Kuan, Wen Bin Zolkifli, Nor Azlina Hendra, Rudi Ho, Yin Wan |
| author_facet | Oskoueian, Ehsan Abdullah, Norhani Saad, Wan Zuhainis Omar, Abdul Rahman Ahmad, Syahida Kuan, Wen Bin Zolkifli, Nor Azlina Hendra, Rudi Ho, Yin Wan |
| author_sort | Oskoueian, Ehsan |
| collection | UPM |
| description | A comprehensive study on the phytochemical contents and biological activities of the methanolic extract from different parts of Jatropha curcas Linn. was conducted. The extracts of different plant parts contained various levels of phenolics, flavonoids and saponins. Latex and leaf extracts showed the highest antioxidant activity. Root and latex extracts inhibited the inducible nitric oxide synthase in macrophages RAW 264.7, comparable to L-Nitro-Arginine Methyl Ester (L-NAME), indicating appreciable anti-inflammatory activities. Cytotoxicity assay results indicated the anticancer therapeutic property of the root extract against human colon adenocarcinoma (HT-29) cell line but its cytotoxic effect on human hepatocyte (Chang cell) was high. |
| first_indexed | 2024-03-06T07:53:39Z |
| format | Article |
| id | upm.eprints-22333 |
| institution | Universiti Putra Malaysia |
| last_indexed | 2024-03-06T07:53:39Z |
| publishDate | 2011 |
| publisher | Academic Journals |
| record_format | dspace |
| spelling | upm.eprints-223332015-09-01T02:25:49Z http://psasir.upm.edu.my/id/eprint/22333/ Antioxidant, anti-inflammatory and anticancer activities of methanolic extracts from Jatropha curcas Linn. Oskoueian, Ehsan Abdullah, Norhani Saad, Wan Zuhainis Omar, Abdul Rahman Ahmad, Syahida Kuan, Wen Bin Zolkifli, Nor Azlina Hendra, Rudi Ho, Yin Wan A comprehensive study on the phytochemical contents and biological activities of the methanolic extract from different parts of Jatropha curcas Linn. was conducted. The extracts of different plant parts contained various levels of phenolics, flavonoids and saponins. Latex and leaf extracts showed the highest antioxidant activity. Root and latex extracts inhibited the inducible nitric oxide synthase in macrophages RAW 264.7, comparable to L-Nitro-Arginine Methyl Ester (L-NAME), indicating appreciable anti-inflammatory activities. Cytotoxicity assay results indicated the anticancer therapeutic property of the root extract against human colon adenocarcinoma (HT-29) cell line but its cytotoxic effect on human hepatocyte (Chang cell) was high. Academic Journals 2011-01-04 Article PeerReviewed Oskoueian, Ehsan and Abdullah, Norhani and Saad, Wan Zuhainis and Omar, Abdul Rahman and Ahmad, Syahida and Kuan, Wen Bin and Zolkifli, Nor Azlina and Hendra, Rudi and Ho, Yin Wan (2011) Antioxidant, anti-inflammatory and anticancer activities of methanolic extracts from Jatropha curcas Linn. Journal of Medicinal Plants Research, 5 (1). pp. 49-57. ISSN 1996-0875 http://www.academicjournals.org/journal/JMPR/article-abstract/5FB390415867 |
| spellingShingle | Oskoueian, Ehsan Abdullah, Norhani Saad, Wan Zuhainis Omar, Abdul Rahman Ahmad, Syahida Kuan, Wen Bin Zolkifli, Nor Azlina Hendra, Rudi Ho, Yin Wan Antioxidant, anti-inflammatory and anticancer activities of methanolic extracts from Jatropha curcas Linn. |
| title | Antioxidant, anti-inflammatory and anticancer activities of methanolic extracts from Jatropha curcas Linn. |
| title_full | Antioxidant, anti-inflammatory and anticancer activities of methanolic extracts from Jatropha curcas Linn. |
| title_fullStr | Antioxidant, anti-inflammatory and anticancer activities of methanolic extracts from Jatropha curcas Linn. |
| title_full_unstemmed | Antioxidant, anti-inflammatory and anticancer activities of methanolic extracts from Jatropha curcas Linn. |
| title_short | Antioxidant, anti-inflammatory and anticancer activities of methanolic extracts from Jatropha curcas Linn. |
| title_sort | antioxidant anti inflammatory and anticancer activities of methanolic extracts from jatropha curcas linn |
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