Executive function and attention span in euthymic patients with bipolar 1 disorder.

This is a cross secti onal co mparison study to assess executive function and attention span in euthymic p atients with bipolar 1 disorder. It compares the performance of these two cogn itive domains in 40 patients with bipolar 1 disorder to that of 40 healthy normal subjects using Trail Maki ng (TM...

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Main Authors: Ibrahim, Normala, Abdul Rahman, Abdul Hamid, Baharuddin, Azlin, Nik Jaafar, Nik Ruzyanei, Zakaria, Hazli, Azhar Shah, Shamsul
Format: Article
Language:English
English
Published: Malaysian Medical Association 2011
Online Access:http://psasir.upm.edu.my/id/eprint/24399/1/Executive%20function%20and%20attention%20span%20in%20euthymic%20patients%20with%20bipolar%201%20disorder.pdf
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author Ibrahim, Normala
Abdul Rahman, Abdul Hamid
Baharuddin, Azlin
Nik Jaafar, Nik Ruzyanei
Zakaria, Hazli
Azhar Shah, Shamsul
author_facet Ibrahim, Normala
Abdul Rahman, Abdul Hamid
Baharuddin, Azlin
Nik Jaafar, Nik Ruzyanei
Zakaria, Hazli
Azhar Shah, Shamsul
author_sort Ibrahim, Normala
collection UPM
description This is a cross secti onal co mparison study to assess executive function and attention span in euthymic p atients with bipolar 1 disorder. It compares the performance of these two cogn itive domains in 40 patients with bipolar 1 disorder to that of 40 healthy normal subjects using Trail Maki ng (TMT), Digit Span (Forward and Backward) and Ver bal Fluency (VF) tests. The association between demographic, clinical characteristics and performance in all tests were examined. Patients wit h bipola r illness showed significant impairment with moderate to large e ffect siz es (VF= 0.67, TMT A= 0.52, TMT B = 0.81, Digit Forward= 0.97, Digit ba ckward= 1.10) in all tasks of executive and atte ntion functioning. These impairments a re observed in the absence of active mood symptoms while duration and severity of illness are not found to have an e ffect on both cognitive domains. Medications received by patients with bipolar disorder have significant association with performance on executive tasks. The results of this study add on to the existing global evidence of cognitive impair ment in bipolar illness despite its cross cultural differences. Its presenc e in the absence of mania, depression or mixed episode indicates that cognitive impairmen t is stable even af ter symptoms recovery.
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spelling upm.eprints-243992015-09-23T01:58:11Z http://psasir.upm.edu.my/id/eprint/24399/ Executive function and attention span in euthymic patients with bipolar 1 disorder. Ibrahim, Normala Abdul Rahman, Abdul Hamid Baharuddin, Azlin Nik Jaafar, Nik Ruzyanei Zakaria, Hazli Azhar Shah, Shamsul This is a cross secti onal co mparison study to assess executive function and attention span in euthymic p atients with bipolar 1 disorder. It compares the performance of these two cogn itive domains in 40 patients with bipolar 1 disorder to that of 40 healthy normal subjects using Trail Maki ng (TMT), Digit Span (Forward and Backward) and Ver bal Fluency (VF) tests. The association between demographic, clinical characteristics and performance in all tests were examined. Patients wit h bipola r illness showed significant impairment with moderate to large e ffect siz es (VF= 0.67, TMT A= 0.52, TMT B = 0.81, Digit Forward= 0.97, Digit ba ckward= 1.10) in all tasks of executive and atte ntion functioning. These impairments a re observed in the absence of active mood symptoms while duration and severity of illness are not found to have an e ffect on both cognitive domains. Medications received by patients with bipolar disorder have significant association with performance on executive tasks. The results of this study add on to the existing global evidence of cognitive impair ment in bipolar illness despite its cross cultural differences. Its presenc e in the absence of mania, depression or mixed episode indicates that cognitive impairmen t is stable even af ter symptoms recovery. Malaysian Medical Association 2011 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24399/1/Executive%20function%20and%20attention%20span%20in%20euthymic%20patients%20with%20bipolar%201%20disorder.pdf Ibrahim, Normala and Abdul Rahman, Abdul Hamid and Baharuddin, Azlin and Nik Jaafar, Nik Ruzyanei and Zakaria, Hazli and Azhar Shah, Shamsul (2011) Executive function and attention span in euthymic patients with bipolar 1 disorder. Medical Journal of Malaysia, 65 (3). pp. 192-196. ISSN 0300-5283 http://www.e-mjm.org/ English
spellingShingle Ibrahim, Normala
Abdul Rahman, Abdul Hamid
Baharuddin, Azlin
Nik Jaafar, Nik Ruzyanei
Zakaria, Hazli
Azhar Shah, Shamsul
Executive function and attention span in euthymic patients with bipolar 1 disorder.
title Executive function and attention span in euthymic patients with bipolar 1 disorder.
title_full Executive function and attention span in euthymic patients with bipolar 1 disorder.
title_fullStr Executive function and attention span in euthymic patients with bipolar 1 disorder.
title_full_unstemmed Executive function and attention span in euthymic patients with bipolar 1 disorder.
title_short Executive function and attention span in euthymic patients with bipolar 1 disorder.
title_sort executive function and attention span in euthymic patients with bipolar 1 disorder
url http://psasir.upm.edu.my/id/eprint/24399/1/Executive%20function%20and%20attention%20span%20in%20euthymic%20patients%20with%20bipolar%201%20disorder.pdf
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