The prevalence of ESBLs producing Klebsiella pneumoniae isolates in some major hospitals, Iran.
Aims of this study were to investigate on antibiotic resistance and molecular epidemiology of K.pneumoniae producing ESBLs isolates of respiratory tract infections in some major hospitals in Iran. K.pneumonaie were obtained of patients with RTI. K. pneumoniae producing ESBLs detected by screening, c...
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| Format: | Article |
| Language: | English English |
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Bentham Science Publishers
2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/24562/1/The%20prevalence%20of%20ESBLs%20producing%20Klebsiella%20pneumoniae%20isolates%20in%20some%20major%20hospitals.pdf |
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| author | Ghofourian, Sobhan Sekawi, Zamberi Sadeghifard, Nourkhoda Mohebi, Reza Neela, Vasantha Kumari Maleki, Abbas Hematian, Ali Rhabar, Mohamad Raftari, Mohamad Ranjbar, Reza |
| author_facet | Ghofourian, Sobhan Sekawi, Zamberi Sadeghifard, Nourkhoda Mohebi, Reza Neela, Vasantha Kumari Maleki, Abbas Hematian, Ali Rhabar, Mohamad Raftari, Mohamad Ranjbar, Reza |
| author_sort | Ghofourian, Sobhan |
| collection | UPM |
| description | Aims of this study were to investigate on antibiotic resistance and molecular epidemiology of K.pneumoniae producing ESBLs isolates of respiratory tract infections in some major hospitals in Iran. K.pneumonaie were obtained of patients with RTI. K. pneumoniae producing ESBLs detected by screening, confirming and PCR methods. During the 12-month period, a total of one hundred and thirteen of K.pneumoniae were found from RTI in three cities in different region of Iran which Sixty seven strains (59.2%) were ESBLs producer. In Ilam hospitals, seventeen strains (43.6%), in Milad hospital, thirty-seven strains (74%) and in Emam Reza hospital, thirteen strains (54.2%) were ESBLs producer. The findings showed that among sixty-seven K.pneumoniae producing ESBLs, Sixty-three strains (94%) were positive for blaSHV, eleven strains (16.4%) contained blaTEM and sixteen strains (23.9%) harbored blaCTX-M. Imipenem was found as an effectiveness antibiotic. In the current study, Majority of the ESBLs production had occurred in Milad hospital in Tehran (74%). In conclusion, spreading ESBL-producing strains is a concern, as it causes limitations to the antimicrobial agents for optimal treatment of patients. |
| first_indexed | 2024-03-06T08:00:13Z |
| format | Article |
| id | upm.eprints-24562 |
| institution | Universiti Putra Malaysia |
| language | English English |
| last_indexed | 2024-03-06T08:00:13Z |
| publishDate | 2011 |
| publisher | Bentham Science Publishers |
| record_format | dspace |
| spelling | upm.eprints-245622015-11-26T08:56:25Z http://psasir.upm.edu.my/id/eprint/24562/ The prevalence of ESBLs producing Klebsiella pneumoniae isolates in some major hospitals, Iran. Ghofourian, Sobhan Sekawi, Zamberi Sadeghifard, Nourkhoda Mohebi, Reza Neela, Vasantha Kumari Maleki, Abbas Hematian, Ali Rhabar, Mohamad Raftari, Mohamad Ranjbar, Reza Aims of this study were to investigate on antibiotic resistance and molecular epidemiology of K.pneumoniae producing ESBLs isolates of respiratory tract infections in some major hospitals in Iran. K.pneumonaie were obtained of patients with RTI. K. pneumoniae producing ESBLs detected by screening, confirming and PCR methods. During the 12-month period, a total of one hundred and thirteen of K.pneumoniae were found from RTI in three cities in different region of Iran which Sixty seven strains (59.2%) were ESBLs producer. In Ilam hospitals, seventeen strains (43.6%), in Milad hospital, thirty-seven strains (74%) and in Emam Reza hospital, thirteen strains (54.2%) were ESBLs producer. The findings showed that among sixty-seven K.pneumoniae producing ESBLs, Sixty-three strains (94%) were positive for blaSHV, eleven strains (16.4%) contained blaTEM and sixteen strains (23.9%) harbored blaCTX-M. Imipenem was found as an effectiveness antibiotic. In the current study, Majority of the ESBLs production had occurred in Milad hospital in Tehran (74%). In conclusion, spreading ESBL-producing strains is a concern, as it causes limitations to the antimicrobial agents for optimal treatment of patients. Bentham Science Publishers 2011 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24562/1/The%20prevalence%20of%20ESBLs%20producing%20Klebsiella%20pneumoniae%20isolates%20in%20some%20major%20hospitals.pdf Ghofourian, Sobhan and Sekawi, Zamberi and Sadeghifard, Nourkhoda and Mohebi, Reza and Neela, Vasantha Kumari and Maleki, Abbas and Hematian, Ali and Rhabar, Mohamad and Raftari, Mohamad and Ranjbar, Reza (2011) The prevalence of ESBLs producing Klebsiella pneumoniae isolates in some major hospitals, Iran. Open Microbiology Journal, 5. pp. 91-95. ISSN 1874-2858 10.2174/1874285801105010091 English |
| spellingShingle | Ghofourian, Sobhan Sekawi, Zamberi Sadeghifard, Nourkhoda Mohebi, Reza Neela, Vasantha Kumari Maleki, Abbas Hematian, Ali Rhabar, Mohamad Raftari, Mohamad Ranjbar, Reza The prevalence of ESBLs producing Klebsiella pneumoniae isolates in some major hospitals, Iran. |
| title | The prevalence of ESBLs producing Klebsiella pneumoniae isolates in some major hospitals, Iran. |
| title_full | The prevalence of ESBLs producing Klebsiella pneumoniae isolates in some major hospitals, Iran. |
| title_fullStr | The prevalence of ESBLs producing Klebsiella pneumoniae isolates in some major hospitals, Iran. |
| title_full_unstemmed | The prevalence of ESBLs producing Klebsiella pneumoniae isolates in some major hospitals, Iran. |
| title_short | The prevalence of ESBLs producing Klebsiella pneumoniae isolates in some major hospitals, Iran. |
| title_sort | prevalence of esbls producing klebsiella pneumoniae isolates in some major hospitals iran |
| url | http://psasir.upm.edu.my/id/eprint/24562/1/The%20prevalence%20of%20ESBLs%20producing%20Klebsiella%20pneumoniae%20isolates%20in%20some%20major%20hospitals.pdf |
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