Nutritional status and the use of protease inhibitors among HIV-infected children in Klang Valley, Malaysia
This study determined the association between nutritional status and the use of protease inhibitors (PI) containing regimen among HIV-infected children receiving treatment at the referral centres in Klang Valley. A total of 95 children currently on antiretroviral (ARV) therapy, aged one to eighteen...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/24590/1/Nutritional%20Status%20and%20the%20Use%20of%20Protease%20Inhibitors%20Among%20Hiv-infected%20Children.pdf |
| _version_ | 1825925602003124224 |
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| author | Mohd Taib, Mohd Nasir Yeo, J. Lee, Mary Huang Soo Koh, M. T. Mohd Razali, Kamarul Azhar Khor, Geok Lin |
| author_facet | Mohd Taib, Mohd Nasir Yeo, J. Lee, Mary Huang Soo Koh, M. T. Mohd Razali, Kamarul Azhar Khor, Geok Lin |
| author_sort | Mohd Taib, Mohd Nasir |
| collection | UPM |
| description | This study determined the association between nutritional status and the use of protease inhibitors (PI) containing regimen among HIV-infected children receiving treatment at the referral centres in Klang Valley. A total of 95 children currently on antiretroviral (ARV) therapy, aged one to eighteen years, were recruited using purposive sampling. Demographic data, anthropometric measurements, medical history, were collected using a structured questionnaire. Serum micronutrients levels and lipid profile were also examined using blood samples. Mean age was 8.8 3.9 years and 44.2% were on PI. Age (2=10.351,
p = .006), weight-for-age ( 2 = 6.567, p = .010), serum selenium ( 2 = 4.225, p = .040) and HDL-C (2=7.539, p=.006) were significantly associated with the use of PI. Fewer children on PI were deficient in selenium as compared to those not on PI. On the contrary, more children on PI were underweight and had low HDL-C. The use of PI was found to have both positive and negative effects with better selenium level but poorer HDL-C level and weight status. |
| first_indexed | 2024-03-06T08:00:18Z |
| format | Article |
| id | upm.eprints-24590 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T08:00:18Z |
| publishDate | 2011 |
| publisher | Faculty of Medicine and Health Sciences, Universiti Putra Malaysia |
| record_format | dspace |
| spelling | upm.eprints-245902015-09-08T04:00:15Z http://psasir.upm.edu.my/id/eprint/24590/ Nutritional status and the use of protease inhibitors among HIV-infected children in Klang Valley, Malaysia Mohd Taib, Mohd Nasir Yeo, J. Lee, Mary Huang Soo Koh, M. T. Mohd Razali, Kamarul Azhar Khor, Geok Lin This study determined the association between nutritional status and the use of protease inhibitors (PI) containing regimen among HIV-infected children receiving treatment at the referral centres in Klang Valley. A total of 95 children currently on antiretroviral (ARV) therapy, aged one to eighteen years, were recruited using purposive sampling. Demographic data, anthropometric measurements, medical history, were collected using a structured questionnaire. Serum micronutrients levels and lipid profile were also examined using blood samples. Mean age was 8.8 3.9 years and 44.2% were on PI. Age (2=10.351, p = .006), weight-for-age ( 2 = 6.567, p = .010), serum selenium ( 2 = 4.225, p = .040) and HDL-C (2=7.539, p=.006) were significantly associated with the use of PI. Fewer children on PI were deficient in selenium as compared to those not on PI. On the contrary, more children on PI were underweight and had low HDL-C. The use of PI was found to have both positive and negative effects with better selenium level but poorer HDL-C level and weight status. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2011 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24590/1/Nutritional%20Status%20and%20the%20Use%20of%20Protease%20Inhibitors%20Among%20Hiv-infected%20Children.pdf Mohd Taib, Mohd Nasir and Yeo, J. and Lee, Mary Huang Soo and Koh, M. T. and Mohd Razali, Kamarul Azhar and Khor, Geok Lin (2011) Nutritional status and the use of protease inhibitors among HIV-infected children in Klang Valley, Malaysia. Malaysian Journal of Medicine and Health Sciences, 7 (2 ). 73 -79. ISSN 1675-8544 http://www.medic.upm.edu.my/dokumen/FKUSK1_MJMHS_2011V07N2_OP08.pdf |
| spellingShingle | Mohd Taib, Mohd Nasir Yeo, J. Lee, Mary Huang Soo Koh, M. T. Mohd Razali, Kamarul Azhar Khor, Geok Lin Nutritional status and the use of protease inhibitors among HIV-infected children in Klang Valley, Malaysia |
| title | Nutritional status and the use of protease inhibitors among HIV-infected children in Klang Valley, Malaysia |
| title_full | Nutritional status and the use of protease inhibitors among HIV-infected children in Klang Valley, Malaysia |
| title_fullStr | Nutritional status and the use of protease inhibitors among HIV-infected children in Klang Valley, Malaysia |
| title_full_unstemmed | Nutritional status and the use of protease inhibitors among HIV-infected children in Klang Valley, Malaysia |
| title_short | Nutritional status and the use of protease inhibitors among HIV-infected children in Klang Valley, Malaysia |
| title_sort | nutritional status and the use of protease inhibitors among hiv infected children in klang valley malaysia |
| url | http://psasir.upm.edu.my/id/eprint/24590/1/Nutritional%20Status%20and%20the%20Use%20of%20Protease%20Inhibitors%20Among%20Hiv-infected%20Children.pdf |
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