Effects of henna (Lawsoniainermis) on the apoptotic pathway of human liver carcinoma cell lines

This study was conducted to determine the effect of henna (extract and essential oil) on the apoptotic phenomena in a human liver cancer cell lines, HepG2. It was determined by using TUNEL assay to investigate their mechanism of action and the observations were done by using Fluoresence Microscope a...

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Main Authors: Endrini, Susi, Rahmat, Asmah, Ismail, Patimah, Yap, Taufiq Yun Hin, Othman, Fauziah
Format: Article
Language:English
Published: American-Eurasian Network for Scientific Information 2011
Online Access:http://psasir.upm.edu.my/id/eprint/24669/1/Effects%20of%20henna.pdf
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author Endrini, Susi
Rahmat, Asmah
Ismail, Patimah
Yap, Taufiq Yun Hin
Othman, Fauziah
author_facet Endrini, Susi
Rahmat, Asmah
Ismail, Patimah
Yap, Taufiq Yun Hin
Othman, Fauziah
author_sort Endrini, Susi
collection UPM
description This study was conducted to determine the effect of henna (extract and essential oil) on the apoptotic phenomena in a human liver cancer cell lines, HepG2. It was determined by using TUNEL assay to investigate their mechanism of action and the observations were done by using Fluoresence Microscope and Confocal Laser Scanning Microscope. Results showed that the apoptotic phenomena induced by henna extract and the essential oil of henna. Many apoptotic bodies, DNA fragmentation and chromatin condensation were observed in the treated groups through the Fluoresence Microscope and Confocal Laser Scanning Microscope. In conclusion, henna may induce apoptosis in HepG2 cell lines.
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spelling upm.eprints-246692016-11-28T04:09:53Z http://psasir.upm.edu.my/id/eprint/24669/ Effects of henna (Lawsoniainermis) on the apoptotic pathway of human liver carcinoma cell lines Endrini, Susi Rahmat, Asmah Ismail, Patimah Yap, Taufiq Yun Hin Othman, Fauziah This study was conducted to determine the effect of henna (extract and essential oil) on the apoptotic phenomena in a human liver cancer cell lines, HepG2. It was determined by using TUNEL assay to investigate their mechanism of action and the observations were done by using Fluoresence Microscope and Confocal Laser Scanning Microscope. Results showed that the apoptotic phenomena induced by henna extract and the essential oil of henna. Many apoptotic bodies, DNA fragmentation and chromatin condensation were observed in the treated groups through the Fluoresence Microscope and Confocal Laser Scanning Microscope. In conclusion, henna may induce apoptosis in HepG2 cell lines. American-Eurasian Network for Scientific Information 2011 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24669/1/Effects%20of%20henna.pdf Endrini, Susi and Rahmat, Asmah and Ismail, Patimah and Yap, Taufiq Yun Hin and Othman, Fauziah (2011) Effects of henna (Lawsoniainermis) on the apoptotic pathway of human liver carcinoma cell lines. Journal of Applied Sciences Research, 7 (3). pp. 321-326. ISSN 1816-157X http://www.aensiweb.com/old/jasr/jasr_march_2011.html
spellingShingle Endrini, Susi
Rahmat, Asmah
Ismail, Patimah
Yap, Taufiq Yun Hin
Othman, Fauziah
Effects of henna (Lawsoniainermis) on the apoptotic pathway of human liver carcinoma cell lines
title Effects of henna (Lawsoniainermis) on the apoptotic pathway of human liver carcinoma cell lines
title_full Effects of henna (Lawsoniainermis) on the apoptotic pathway of human liver carcinoma cell lines
title_fullStr Effects of henna (Lawsoniainermis) on the apoptotic pathway of human liver carcinoma cell lines
title_full_unstemmed Effects of henna (Lawsoniainermis) on the apoptotic pathway of human liver carcinoma cell lines
title_short Effects of henna (Lawsoniainermis) on the apoptotic pathway of human liver carcinoma cell lines
title_sort effects of henna lawsoniainermis on the apoptotic pathway of human liver carcinoma cell lines
url http://psasir.upm.edu.my/id/eprint/24669/1/Effects%20of%20henna.pdf
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