Determination and optimization of flavonoid and extract yield from brown mango using response surface methodology.

The optimum extraction conditions to obtain the highest flavonoid content and extract yield from Mangifera pajang pericarp (MPP) were analyzed using response surface methodology (RSM). A full factorial central composite design was used to investigate the effects of ethanol concentration (20-80%), te...

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Main Authors: Prasad, K. Nagendra, Kin, Weng Kong, Ramanan, Ramakrishnan Nagasundara, Azlan, Azrina, Ismail, Amin
Format: Article
Language:English
English
Published: Taylor & Francis 2012
Online Access:http://psasir.upm.edu.my/id/eprint/24716/1/Determination%20and%20optimization%20of%20flavonoid%20and%20extract%20yield%20from%20brown%20mango%20using%20response%20surface%20methodology.pdf
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author Prasad, K. Nagendra
Kin, Weng Kong
Ramanan, Ramakrishnan Nagasundara
Azlan, Azrina
Ismail, Amin
author_facet Prasad, K. Nagendra
Kin, Weng Kong
Ramanan, Ramakrishnan Nagasundara
Azlan, Azrina
Ismail, Amin
author_sort Prasad, K. Nagendra
collection UPM
description The optimum extraction conditions to obtain the highest flavonoid content and extract yield from Mangifera pajang pericarp (MPP) were analyzed using response surface methodology (RSM). A full factorial central composite design was used to investigate the effects of ethanol concentration (20-80%), temperature (30-65°C) and liquid to solid ratio (20-50 mL/g) on the recovery of extract yield and flavonoids. A second order polynomial model produced a satisfactory fitting of the experimental data with regard to extract yield (R 2 = 0.9890, p < 0.0001) and flavonoids (R 2 = 0.9652, p < 0.0001). The optimum conditions to obtain higher extract yield, were 54%, 50°C, and 42.4 mL/g, while for flavonoids were 68%, 57°C, and 20.2 mL/g, respectively. The experimental values agreed with those predicted with 99% and 96% confidence interval for extract yield and flavonoids respectively. This indicates the suitability of RSM in optimizing the extraction of flavonoids and extract yield from MPP.
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spelling upm.eprints-247162015-10-28T06:40:17Z http://psasir.upm.edu.my/id/eprint/24716/ Determination and optimization of flavonoid and extract yield from brown mango using response surface methodology. Prasad, K. Nagendra Kin, Weng Kong Ramanan, Ramakrishnan Nagasundara Azlan, Azrina Ismail, Amin The optimum extraction conditions to obtain the highest flavonoid content and extract yield from Mangifera pajang pericarp (MPP) were analyzed using response surface methodology (RSM). A full factorial central composite design was used to investigate the effects of ethanol concentration (20-80%), temperature (30-65°C) and liquid to solid ratio (20-50 mL/g) on the recovery of extract yield and flavonoids. A second order polynomial model produced a satisfactory fitting of the experimental data with regard to extract yield (R 2 = 0.9890, p < 0.0001) and flavonoids (R 2 = 0.9652, p < 0.0001). The optimum conditions to obtain higher extract yield, were 54%, 50°C, and 42.4 mL/g, while for flavonoids were 68%, 57°C, and 20.2 mL/g, respectively. The experimental values agreed with those predicted with 99% and 96% confidence interval for extract yield and flavonoids respectively. This indicates the suitability of RSM in optimizing the extraction of flavonoids and extract yield from MPP. Taylor & Francis 2012-01 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24716/1/Determination%20and%20optimization%20of%20flavonoid%20and%20extract%20yield%20from%20brown%20mango%20using%20response%20surface%20methodology.pdf Prasad, K. Nagendra and Kin, Weng Kong and Ramanan, Ramakrishnan Nagasundara and Azlan, Azrina and Ismail, Amin (2012) Determination and optimization of flavonoid and extract yield from brown mango using response surface methodology. Separation Science and Technology , 47 (1). pp. 73-80. ISSN 0149-6395; ESSN:1520-5754 http://www.tandf.co.uk/ 10.1080/01496395.2011.606257 English
spellingShingle Prasad, K. Nagendra
Kin, Weng Kong
Ramanan, Ramakrishnan Nagasundara
Azlan, Azrina
Ismail, Amin
Determination and optimization of flavonoid and extract yield from brown mango using response surface methodology.
title Determination and optimization of flavonoid and extract yield from brown mango using response surface methodology.
title_full Determination and optimization of flavonoid and extract yield from brown mango using response surface methodology.
title_fullStr Determination and optimization of flavonoid and extract yield from brown mango using response surface methodology.
title_full_unstemmed Determination and optimization of flavonoid and extract yield from brown mango using response surface methodology.
title_short Determination and optimization of flavonoid and extract yield from brown mango using response surface methodology.
title_sort determination and optimization of flavonoid and extract yield from brown mango using response surface methodology
url http://psasir.upm.edu.my/id/eprint/24716/1/Determination%20and%20optimization%20of%20flavonoid%20and%20extract%20yield%20from%20brown%20mango%20using%20response%20surface%20methodology.pdf
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