Topical piroxicam in vitro release and in vivo anti-inflammatory and analgesic effects from palm oil esters-based nanocream.
During recent years, there has been growing interest in use of topical vehicle systems to assist in drug permeation through the skin. Drugs of interest are usually those that are problematic when given orally, such as piroxicam, a highly effective anti-inflammatory, anti-pyretic, and analgesic, but...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2010
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| Online Access: | http://psasir.upm.edu.my/id/eprint/24756/1/Topical%20piroxicam%20in%20vitro%20release%20and%20in%20vivo%20anti.pdf |
| _version_ | 1796970623306563584 |
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| author | Abdulkarim, Muthanna Fawzy Abdullah, Ghassan Zuhair Chitneni, Mallikarjun M. Salman, Ibrahim Ameer, Omar Ziad Yam, Mun Fee Mahdi, Elrashid Saleh Sattar, Munavvar A. Basri, Mahiran M. Noor, Azmin |
| author_facet | Abdulkarim, Muthanna Fawzy Abdullah, Ghassan Zuhair Chitneni, Mallikarjun M. Salman, Ibrahim Ameer, Omar Ziad Yam, Mun Fee Mahdi, Elrashid Saleh Sattar, Munavvar A. Basri, Mahiran M. Noor, Azmin |
| author_sort | Abdulkarim, Muthanna Fawzy |
| collection | UPM |
| description | During recent years, there has been growing interest in use of topical vehicle systems to assist in drug permeation through the skin. Drugs of interest are usually those that are problematic when given orally, such as piroxicam, a highly effective anti-inflammatory, anti-pyretic, and analgesic, but with the adverse effect of causing gastrointestinal ulcers. The present study investigated the in vitro and in vivo pharmacodynamic activity of a newly synthesized palm oil esters (POEs)-based nanocream containing piroxicam for topical delivery. |
| first_indexed | 2024-03-06T08:00:48Z |
| format | Article |
| id | upm.eprints-24756 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T08:00:48Z |
| publishDate | 2010 |
| publisher | Dove Medical Press |
| record_format | dspace |
| spelling | upm.eprints-247562015-11-05T08:54:56Z http://psasir.upm.edu.my/id/eprint/24756/ Topical piroxicam in vitro release and in vivo anti-inflammatory and analgesic effects from palm oil esters-based nanocream. Abdulkarim, Muthanna Fawzy Abdullah, Ghassan Zuhair Chitneni, Mallikarjun M. Salman, Ibrahim Ameer, Omar Ziad Yam, Mun Fee Mahdi, Elrashid Saleh Sattar, Munavvar A. Basri, Mahiran M. Noor, Azmin During recent years, there has been growing interest in use of topical vehicle systems to assist in drug permeation through the skin. Drugs of interest are usually those that are problematic when given orally, such as piroxicam, a highly effective anti-inflammatory, anti-pyretic, and analgesic, but with the adverse effect of causing gastrointestinal ulcers. The present study investigated the in vitro and in vivo pharmacodynamic activity of a newly synthesized palm oil esters (POEs)-based nanocream containing piroxicam for topical delivery. Dove Medical Press 2010 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24756/1/Topical%20piroxicam%20in%20vitro%20release%20and%20in%20vivo%20anti.pdf Abdulkarim, Muthanna Fawzy and Abdullah, Ghassan Zuhair and Chitneni, Mallikarjun and M. Salman, Ibrahim and Ameer, Omar Ziad and Yam, Mun Fee and Mahdi, Elrashid Saleh and Sattar, Munavvar A. and Basri, Mahiran and M. Noor, Azmin (2010) Topical piroxicam in vitro release and in vivo anti-inflammatory and analgesic effects from palm oil esters-based nanocream. International Journal of Nanomedicine, 5. pp. 915-924. ISSN 1176-9114; ESSN:1178-2013 http://www.dovepress.com/international-journal-of-nanomedicine-journal 10.2147/IJN.S13305 |
| spellingShingle | Abdulkarim, Muthanna Fawzy Abdullah, Ghassan Zuhair Chitneni, Mallikarjun M. Salman, Ibrahim Ameer, Omar Ziad Yam, Mun Fee Mahdi, Elrashid Saleh Sattar, Munavvar A. Basri, Mahiran M. Noor, Azmin Topical piroxicam in vitro release and in vivo anti-inflammatory and analgesic effects from palm oil esters-based nanocream. |
| title | Topical piroxicam in vitro release and in vivo anti-inflammatory and analgesic effects from palm oil esters-based nanocream. |
| title_full | Topical piroxicam in vitro release and in vivo anti-inflammatory and analgesic effects from palm oil esters-based nanocream. |
| title_fullStr | Topical piroxicam in vitro release and in vivo anti-inflammatory and analgesic effects from palm oil esters-based nanocream. |
| title_full_unstemmed | Topical piroxicam in vitro release and in vivo anti-inflammatory and analgesic effects from palm oil esters-based nanocream. |
| title_short | Topical piroxicam in vitro release and in vivo anti-inflammatory and analgesic effects from palm oil esters-based nanocream. |
| title_sort | topical piroxicam in vitro release and in vivo anti inflammatory and analgesic effects from palm oil esters based nanocream |
| url | http://psasir.upm.edu.my/id/eprint/24756/1/Topical%20piroxicam%20in%20vitro%20release%20and%20in%20vivo%20anti.pdf |
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