Microfluidics-based lab-on-chip systems in DNA-based biosensing: An overview.

Microfluidics-based lab-on-chip (LOC) systems are an active research area that is revolutionising high-throughput sequencing for the fast, sensitive and accurate detection of a variety of pathogens. LOCs also serve as portable diagnostic tools. The devices provide optimum control of nanolitre volume...

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Main Authors: Dutse, Sabo Wada, Yusof, Nor Azah
Format: Article
Language:English
English
Published: MDPI 2011
Online Access:http://psasir.upm.edu.my/id/eprint/24880/1/Microfluidics.pdf
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author Dutse, Sabo Wada
Yusof, Nor Azah
author_facet Dutse, Sabo Wada
Yusof, Nor Azah
author_sort Dutse, Sabo Wada
collection UPM
description Microfluidics-based lab-on-chip (LOC) systems are an active research area that is revolutionising high-throughput sequencing for the fast, sensitive and accurate detection of a variety of pathogens. LOCs also serve as portable diagnostic tools. The devices provide optimum control of nanolitre volumes of fluids and integrate various bioassay operations that allow the devices to rapidly sense pathogenic threat agents for environmental monitoring. LOC systems, such as microfluidic biochips, offer advantages compared to conventional identification procedures that are tedious, expensive and time consuming. This paper aims to provide a broad overview of the need for devices that are easy to operate, sensitive, fast, portable and sufficiently reliable to be used as complementary tools for the control of pathogenic agents that damage the environment.
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spelling upm.eprints-248802015-10-08T08:50:04Z http://psasir.upm.edu.my/id/eprint/24880/ Microfluidics-based lab-on-chip systems in DNA-based biosensing: An overview. Dutse, Sabo Wada Yusof, Nor Azah Microfluidics-based lab-on-chip (LOC) systems are an active research area that is revolutionising high-throughput sequencing for the fast, sensitive and accurate detection of a variety of pathogens. LOCs also serve as portable diagnostic tools. The devices provide optimum control of nanolitre volumes of fluids and integrate various bioassay operations that allow the devices to rapidly sense pathogenic threat agents for environmental monitoring. LOC systems, such as microfluidic biochips, offer advantages compared to conventional identification procedures that are tedious, expensive and time consuming. This paper aims to provide a broad overview of the need for devices that are easy to operate, sensitive, fast, portable and sufficiently reliable to be used as complementary tools for the control of pathogenic agents that damage the environment. MDPI 2011-06 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24880/1/Microfluidics.pdf Dutse, Sabo Wada and Yusof, Nor Azah (2011) Microfluidics-based lab-on-chip systems in DNA-based biosensing: An overview. Sensors, 11 (6). pp. 5754-5768. ISSN 1424-8220; ESSN:1424-8220 http://www.mdpi.com/ 10.3390/s110605754 English
spellingShingle Dutse, Sabo Wada
Yusof, Nor Azah
Microfluidics-based lab-on-chip systems in DNA-based biosensing: An overview.
title Microfluidics-based lab-on-chip systems in DNA-based biosensing: An overview.
title_full Microfluidics-based lab-on-chip systems in DNA-based biosensing: An overview.
title_fullStr Microfluidics-based lab-on-chip systems in DNA-based biosensing: An overview.
title_full_unstemmed Microfluidics-based lab-on-chip systems in DNA-based biosensing: An overview.
title_short Microfluidics-based lab-on-chip systems in DNA-based biosensing: An overview.
title_sort microfluidics based lab on chip systems in dna based biosensing an overview
url http://psasir.upm.edu.my/id/eprint/24880/1/Microfluidics.pdf
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