Artomandin, a new xanthone from Artocarpus kemando (Moraceae).

A new furanodihydrobenzoxanthone, artomandin (1), together with three other flavonoid derivatives, artoindonesianin C (2), artonol B (3), and artochamin A (4), as well as β-sitosterol (5) were isolated from the stem bark of Artocarpus kemando. The structures of these compounds were determined on the...

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Bibliographic Details
Main Authors: Ee, Gwendoline Cheng Lian, Siow, Hwa Teo, Rahmani, Mawardi, Chan, Kiang Lim, Yang, Mooi Lim, Go, Rusea
Format: Article
Language:English
English
Published: Taylor & Francis 2011
Online Access:http://psasir.upm.edu.my/id/eprint/24886/1/Artomandin.pdf
Description
Summary:A new furanodihydrobenzoxanthone, artomandin (1), together with three other flavonoid derivatives, artoindonesianin C (2), artonol B (3), and artochamin A (4), as well as β-sitosterol (5) were isolated from the stem bark of Artocarpus kemando. The structures of these compounds were determined on the basis of spectral evidence. All of these compounds displayed inhibition effects to a very susceptible degree in cancer cell line tests. Compound 1 also exhibited significant antioxidant capacity in the free radical 1,1-diphenyl-2-picrylhydrazyl tests.