Chemical constituents of Artocarpus kemando (Moraceae).
The stem bark of Artocarpus kemando furnished 24-methylenecycloartenyl acetate (fatty acyl ester) (1) together with cycloartobiloxanthone (2). Compound 1 was obtained for the first time from this species. Structures of both compounds were determined using NMR and MS analysis. A cytotoxic study showe...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Chemical Publishing Co.
2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/24889/1/Chemical%20constituents%20of%20Artocarpus%20kemando.pdf |
| Summary: | The stem bark of Artocarpus kemando furnished 24-methylenecycloartenyl acetate (fatty acyl ester) (1) together with cycloartobiloxanthone (2). Compound 1 was obtained for the first time from this species. Structures of both compounds were determined using NMR and MS analysis. A cytotoxic study showed that the crude extract of the stem bark of Artocarpus kemando was significantly active against the HL-60 (human promyelocytic leukemia cell) and IMR-32 (human neuroblastoma cell) cell lines. This is the first report on the cyctotoxic activity of Artocarpus kemando.
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