Prenatal screening of down syndrome.
The present invention provides a method using polymerasa chain reaction (PCR) for detecting Down syndrom in the fetus of a pregnant woman by way of determining the increased concentration levels of supeoxide dismutase-1 (SOD-1) gene sequence in maternal extra-cellular body fluid. Accordingly, the pr...
| Main Authors: | , |
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| Format: | Patent |
| Published: |
2006
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| _version_ | 1796970834956386304 |
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| author | Rosli, Rozita Karuppiah, Thilakavathy |
| author_facet | Rosli, Rozita Karuppiah, Thilakavathy |
| author_sort | Rosli, Rozita |
| collection | UPM |
| description | The present invention provides a method using polymerasa chain reaction (PCR) for detecting Down syndrom in the fetus of a pregnant woman by way of determining the increased concentration levels of supeoxide dismutase-1 (SOD-1) gene sequence in maternal extra-cellular body fluid. Accordingly, the present invention provides a method for screening Down syndrom fetus using DNA aplification promers and gene specific probe for specifically amplifying and quantifying superoxide dismutase-1 (SOD-1) gene in a pregnant woman. The invention also relates to a diagnostic kit for carrying out the invention method.
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| first_indexed | 2024-03-06T08:03:59Z |
| format | Patent |
| id | upm.eprints-25874 |
| institution | Universiti Putra Malaysia |
| last_indexed | 2024-03-06T08:03:59Z |
| publishDate | 2006 |
| record_format | dspace |
| spelling | upm.eprints-258742013-10-29T03:22:44Z http://psasir.upm.edu.my/id/eprint/25874/ Prenatal screening of down syndrome. Rosli, Rozita Karuppiah, Thilakavathy The present invention provides a method using polymerasa chain reaction (PCR) for detecting Down syndrom in the fetus of a pregnant woman by way of determining the increased concentration levels of supeoxide dismutase-1 (SOD-1) gene sequence in maternal extra-cellular body fluid. Accordingly, the present invention provides a method for screening Down syndrom fetus using DNA aplification promers and gene specific probe for specifically amplifying and quantifying superoxide dismutase-1 (SOD-1) gene in a pregnant woman. The invention also relates to a diagnostic kit for carrying out the invention method. 2006-04-25 Patent NonPeerReviewed Rozita Rosli (2006) Prenatal screening of down syndrome. UNSPECIFIED. |
| spellingShingle | Rosli, Rozita Karuppiah, Thilakavathy Prenatal screening of down syndrome. |
| title | Prenatal screening of down syndrome.
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| title_full | Prenatal screening of down syndrome.
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| title_fullStr | Prenatal screening of down syndrome.
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| title_full_unstemmed | Prenatal screening of down syndrome.
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| title_short | Prenatal screening of down syndrome.
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| title_sort | prenatal screening of down syndrome |
| work_keys_str_mv | AT roslirozita prenatalscreeningofdownsyndrome AT karuppiahthilakavathy prenatalscreeningofdownsyndrome |