Infectious viruses for the biological control of rice-field rats : rat cytomegalovirus (RCMV) as a suitable candidate for the development of immunocontraceptive vaccines.

A serologic survey of viruses infecting rice-field rats (Rattus argentiventer)in Malaysia was conducted in five different geographic locations. Results indicate that approximately 50% of the rice-field rats were positive for rat crytomegalovirus (RCMV). A lower prevalence rate has been demonstrated...

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Main Authors: Mohd Lila, Mohd Azmi, Lai, Kit Yee, Abdul Rahman, Sheikh Omar, Smith, A. L., Lam, Y. M.
Format: Conference or Workshop Item
Language:English
English
Published: 1999
Online Access:http://psasir.upm.edu.my/id/eprint/27301/1/ID%2027301.pdf
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author Mohd Lila, Mohd Azmi
Lai, Kit Yee
Abdul Rahman, Sheikh Omar
Smith, A. L.
Lam, Y. M.
author_facet Mohd Lila, Mohd Azmi
Lai, Kit Yee
Abdul Rahman, Sheikh Omar
Smith, A. L.
Lam, Y. M.
author_sort Mohd Lila, Mohd Azmi
collection UPM
description A serologic survey of viruses infecting rice-field rats (Rattus argentiventer)in Malaysia was conducted in five different geographic locations. Results indicate that approximately 50% of the rice-field rats were positive for rat crytomegalovirus (RCMV). A lower prevalence rate has been demonstrated fro coronavirus, adenovirus, new rat parvovirus, conventional parvovirus and Theiler's virus. None of the serum samples tested positive for lymphocytic choriomeningitis virus (LCMV), vaccinia virus, Hantaan virus, Seoul virus, pneumonia virus and Sendai virus. RCMV was highly prevalent at different sampling locations. Two different RCMVs have been isolated from the rats. These viruses have been extensively characterised and compared with established RCMV strains of Rattus norvegicus. The new RCMV strains designated RCMV-Sg and RCMV-Kn were different at molecular level but serelogically related. Based on their biological and molcecular characteristics it is likely that the virus could be used as a vehicle to carry immunocontraceptive genes.
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spelling upm.eprints-273012015-04-08T07:37:38Z http://psasir.upm.edu.my/id/eprint/27301/ Infectious viruses for the biological control of rice-field rats : rat cytomegalovirus (RCMV) as a suitable candidate for the development of immunocontraceptive vaccines. Mohd Lila, Mohd Azmi Lai, Kit Yee Abdul Rahman, Sheikh Omar Smith, A. L. Lam, Y. M. A serologic survey of viruses infecting rice-field rats (Rattus argentiventer)in Malaysia was conducted in five different geographic locations. Results indicate that approximately 50% of the rice-field rats were positive for rat crytomegalovirus (RCMV). A lower prevalence rate has been demonstrated fro coronavirus, adenovirus, new rat parvovirus, conventional parvovirus and Theiler's virus. None of the serum samples tested positive for lymphocytic choriomeningitis virus (LCMV), vaccinia virus, Hantaan virus, Seoul virus, pneumonia virus and Sendai virus. RCMV was highly prevalent at different sampling locations. Two different RCMVs have been isolated from the rats. These viruses have been extensively characterised and compared with established RCMV strains of Rattus norvegicus. The new RCMV strains designated RCMV-Sg and RCMV-Kn were different at molecular level but serelogically related. Based on their biological and molcecular characteristics it is likely that the virus could be used as a vehicle to carry immunocontraceptive genes. 1999 Conference or Workshop Item NonPeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/27301/1/ID%2027301.pdf Mohd Lila, Mohd Azmi and Lai, Kit Yee and Abdul Rahman, Sheikh Omar and Smith, A. L. and Lam, Y. M. (1999) Infectious viruses for the biological control of rice-field rats : rat cytomegalovirus (RCMV) as a suitable candidate for the development of immunocontraceptive vaccines. In: Symposium on Biological Control in the Tropics, 18-19 Mar. 1999, Serdang, Selangor. . English
spellingShingle Mohd Lila, Mohd Azmi
Lai, Kit Yee
Abdul Rahman, Sheikh Omar
Smith, A. L.
Lam, Y. M.
Infectious viruses for the biological control of rice-field rats : rat cytomegalovirus (RCMV) as a suitable candidate for the development of immunocontraceptive vaccines.
title Infectious viruses for the biological control of rice-field rats : rat cytomegalovirus (RCMV) as a suitable candidate for the development of immunocontraceptive vaccines.
title_full Infectious viruses for the biological control of rice-field rats : rat cytomegalovirus (RCMV) as a suitable candidate for the development of immunocontraceptive vaccines.
title_fullStr Infectious viruses for the biological control of rice-field rats : rat cytomegalovirus (RCMV) as a suitable candidate for the development of immunocontraceptive vaccines.
title_full_unstemmed Infectious viruses for the biological control of rice-field rats : rat cytomegalovirus (RCMV) as a suitable candidate for the development of immunocontraceptive vaccines.
title_short Infectious viruses for the biological control of rice-field rats : rat cytomegalovirus (RCMV) as a suitable candidate for the development of immunocontraceptive vaccines.
title_sort infectious viruses for the biological control of rice field rats rat cytomegalovirus rcmv as a suitable candidate for the development of immunocontraceptive vaccines
url http://psasir.upm.edu.my/id/eprint/27301/1/ID%2027301.pdf
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