Total synthesis, cytotoxic effects of damnacanthal, nordamnacanthal and related anthraquinone analogues

Total synthesis, cytotoxic effects of damnacanthal, nordamnacanthal and related anthraquinone analogues

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Naturally occurring anthraquinones, damnacanthal (1) and nordamnacanthal (2) were synthesized with modified reaction steps and investigated for their cytotoxicity against the MCF-7 and K-562 cancer cell lines, respectively. Intermediate analogues 2-bromomethyl-1,3-dimethoxyanthraquinone (5, IC 50 =...

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Bibliographic Details
Main Authors:	Akhtar, Muhammad Nadeem, Zareen, Seema, Yeap, Swee Keong, Ho, Wan Yong, Lo, Kong Mun, Hasan, Aurangzeb, Mohammed Alitheen, Noorjahan Banu
Format:	Article
Language:	English
Published:	MDPI 2013
Online Access:	http://psasir.upm.edu.my/id/eprint/28053/1/molecules-18-10042%20%281%29.pdf

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