Using design of experiments methods for assessing peak contact pressure to material properties of soft tissue in human knee

Contact pressure in the knee joint is a key element in the mechanisms of knee pain and osteoarthritis. Assessing the contact pressure in tibiofemoral joint is a challenging mechanical problem due to uncertainty in material properties. In this study, a sensitivity analysis of tibiofemoral peak contac...

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Main Authors: Bahraminasab, Marjan, Jahan, Ali, Sahari, Barkawi, Arumugam, Manohar, Shamsborhan, Mahmoud, Hassan, Mohd Roshdi
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:http://psasir.upm.edu.my/id/eprint/28877/1/Using%20design%20of%20experiments%20methods%20for%20assessing%20peak%20contact%20pressure%20to%20material%20properties%20of%20soft%20tissue%20in%20human%20knee.pdf
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author Bahraminasab, Marjan
Jahan, Ali
Sahari, Barkawi
Arumugam, Manohar
Shamsborhan, Mahmoud
Hassan, Mohd Roshdi
author_facet Bahraminasab, Marjan
Jahan, Ali
Sahari, Barkawi
Arumugam, Manohar
Shamsborhan, Mahmoud
Hassan, Mohd Roshdi
author_sort Bahraminasab, Marjan
collection UPM
description Contact pressure in the knee joint is a key element in the mechanisms of knee pain and osteoarthritis. Assessing the contact pressure in tibiofemoral joint is a challenging mechanical problem due to uncertainty in material properties. In this study, a sensitivity analysis of tibiofemoral peak contact pressure to the material properties of the soft tissue was carried out through fractional factorial and Box-Behnken designs. The cartilage was modeled as linear elastic material, and in addition to its elastic modulus, interaction effects of soft tissue material properties were added compared to previous research. The results indicated that elastic modulus of the cartilage is the most effective factor. Interaction effects of axial/radial modulus with elastic modulus of cartilage, circumferential and axial/radial moduli of meniscus were other influential factors. Furthermore this study showed how design of experiment methods can help designers to reduce the number of finite element analyses and to better interpret the results.
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spelling upm.eprints-288772015-08-25T06:27:18Z http://psasir.upm.edu.my/id/eprint/28877/ Using design of experiments methods for assessing peak contact pressure to material properties of soft tissue in human knee Bahraminasab, Marjan Jahan, Ali Sahari, Barkawi Arumugam, Manohar Shamsborhan, Mahmoud Hassan, Mohd Roshdi Contact pressure in the knee joint is a key element in the mechanisms of knee pain and osteoarthritis. Assessing the contact pressure in tibiofemoral joint is a challenging mechanical problem due to uncertainty in material properties. In this study, a sensitivity analysis of tibiofemoral peak contact pressure to the material properties of the soft tissue was carried out through fractional factorial and Box-Behnken designs. The cartilage was modeled as linear elastic material, and in addition to its elastic modulus, interaction effects of soft tissue material properties were added compared to previous research. The results indicated that elastic modulus of the cartilage is the most effective factor. Interaction effects of axial/radial modulus with elastic modulus of cartilage, circumferential and axial/radial moduli of meniscus were other influential factors. Furthermore this study showed how design of experiment methods can help designers to reduce the number of finite element analyses and to better interpret the results. Hindawi Publishing Corporation 2013 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/28877/1/Using%20design%20of%20experiments%20methods%20for%20assessing%20peak%20contact%20pressure%20to%20material%20properties%20of%20soft%20tissue%20in%20human%20knee.pdf Bahraminasab, Marjan and Jahan, Ali and Sahari, Barkawi and Arumugam, Manohar and Shamsborhan, Mahmoud and Hassan, Mohd Roshdi (2013) Using design of experiments methods for assessing peak contact pressure to material properties of soft tissue in human knee. Journal of Medical Engineering, 2013. art. no. 891759. pp. 1-11. ISSN 2314-5129; ESSN: 2314-5137 http://www.hindawi.com/journals/jme/2013/891759/ 10.1155/2013/891759
spellingShingle Bahraminasab, Marjan
Jahan, Ali
Sahari, Barkawi
Arumugam, Manohar
Shamsborhan, Mahmoud
Hassan, Mohd Roshdi
Using design of experiments methods for assessing peak contact pressure to material properties of soft tissue in human knee
title Using design of experiments methods for assessing peak contact pressure to material properties of soft tissue in human knee
title_full Using design of experiments methods for assessing peak contact pressure to material properties of soft tissue in human knee
title_fullStr Using design of experiments methods for assessing peak contact pressure to material properties of soft tissue in human knee
title_full_unstemmed Using design of experiments methods for assessing peak contact pressure to material properties of soft tissue in human knee
title_short Using design of experiments methods for assessing peak contact pressure to material properties of soft tissue in human knee
title_sort using design of experiments methods for assessing peak contact pressure to material properties of soft tissue in human knee
url http://psasir.upm.edu.my/id/eprint/28877/1/Using%20design%20of%20experiments%20methods%20for%20assessing%20peak%20contact%20pressure%20to%20material%20properties%20of%20soft%20tissue%20in%20human%20knee.pdf
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