Potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in PET oncology examination
Development of the positron emission tomography (PET) diagnostic radiopharmaceutical (18F) fluoro-2-deoxy-D-glucose (18F-FDG) subsequently facilitated the discovery and clinical evaluation of several new tracers as imaging markers for cancer. While 18F-FDG is a widely employed marker for enhanced in...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Universiti Putra Malaysia Press
2016
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/29519/1/03%20JST-0544-2015%20Rev1-%20Hishar%20Hassanr-Review%20Paper.pdf |
| _version_ | 1796971555408838656 |
|---|---|
| author | Hassan, Hishar Price, Roger Ahmad Saad, Fathinul Fikri Lau, Eddie Wing Fai Carpinelli, Assunta Nordin, Abdul Jalil |
| author_facet | Hassan, Hishar Price, Roger Ahmad Saad, Fathinul Fikri Lau, Eddie Wing Fai Carpinelli, Assunta Nordin, Abdul Jalil |
| author_sort | Hassan, Hishar |
| collection | UPM |
| description | Development of the positron emission tomography (PET) diagnostic radiopharmaceutical (18F) fluoro-2-deoxy-D-glucose (18F-FDG) subsequently facilitated the discovery and clinical evaluation of several new tracers as imaging markers for cancer. While 18F-FDG is a widely employed marker for enhanced intracellular glycolysis and metabolic function, one of the newer tracers, (18F)-3’-fluoro-3’ deoxythymidine (18F-FLT), has been developed as a biomarker for cell proliferation. In this review, the potential of 18F-FLT as a biomarker for cancer imaging is discussed. |
| first_indexed | 2024-03-06T08:14:44Z |
| format | Article |
| id | upm.eprints-29519 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T08:14:44Z |
| publishDate | 2016 |
| publisher | Universiti Putra Malaysia Press |
| record_format | dspace |
| spelling | upm.eprints-295192017-11-15T08:12:47Z http://psasir.upm.edu.my/id/eprint/29519/ Potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in PET oncology examination Hassan, Hishar Price, Roger Ahmad Saad, Fathinul Fikri Lau, Eddie Wing Fai Carpinelli, Assunta Nordin, Abdul Jalil Development of the positron emission tomography (PET) diagnostic radiopharmaceutical (18F) fluoro-2-deoxy-D-glucose (18F-FDG) subsequently facilitated the discovery and clinical evaluation of several new tracers as imaging markers for cancer. While 18F-FDG is a widely employed marker for enhanced intracellular glycolysis and metabolic function, one of the newer tracers, (18F)-3’-fluoro-3’ deoxythymidine (18F-FLT), has been developed as a biomarker for cell proliferation. In this review, the potential of 18F-FLT as a biomarker for cancer imaging is discussed. Universiti Putra Malaysia Press 2016 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/29519/1/03%20JST-0544-2015%20Rev1-%20Hishar%20Hassanr-Review%20Paper.pdf Hassan, Hishar and Price, Roger and Ahmad Saad, Fathinul Fikri and Lau, Eddie Wing Fai and Carpinelli, Assunta and Nordin, Abdul Jalil (2016) Potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in PET oncology examination. Pertanika Journal of Science & Technology, 24 (1). pp. 41-52. ISSN 0128-7680; ESSN: 2231-8526 http://www.pertanika.upm.edu.my/Pertanika%20PAPERS/JST%20Vol.%2024%20(1)%20Jan.%202016/03%20JST-0544-2015%20Rev1-%20Hishar%20Hassanr-Review%20Paper.pdf |
| spellingShingle | Hassan, Hishar Price, Roger Ahmad Saad, Fathinul Fikri Lau, Eddie Wing Fai Carpinelli, Assunta Nordin, Abdul Jalil Potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in PET oncology examination |
| title | Potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in PET oncology examination |
| title_full | Potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in PET oncology examination |
| title_fullStr | Potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in PET oncology examination |
| title_full_unstemmed | Potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in PET oncology examination |
| title_short | Potential of 3’-fluoro-3’ deoxythymidine as a cellular proliferation marker in PET oncology examination |
| title_sort | potential of 3 fluoro 3 deoxythymidine as a cellular proliferation marker in pet oncology examination |
| url | http://psasir.upm.edu.my/id/eprint/29519/1/03%20JST-0544-2015%20Rev1-%20Hishar%20Hassanr-Review%20Paper.pdf |
| work_keys_str_mv | AT hassanhishar potentialof3fluoro3deoxythymidineasacellularproliferationmarkerinpetoncologyexamination AT priceroger potentialof3fluoro3deoxythymidineasacellularproliferationmarkerinpetoncologyexamination AT ahmadsaadfathinulfikri potentialof3fluoro3deoxythymidineasacellularproliferationmarkerinpetoncologyexamination AT laueddiewingfai potentialof3fluoro3deoxythymidineasacellularproliferationmarkerinpetoncologyexamination AT carpinelliassunta potentialof3fluoro3deoxythymidineasacellularproliferationmarkerinpetoncologyexamination AT nordinabduljalil potentialof3fluoro3deoxythymidineasacellularproliferationmarkerinpetoncologyexamination |