Dietary non-nutritive factors on molecular targets of colorectal cancer: an update
Colorectal cancer (CRC), a complex multi-step process involving progressive disruption of homeostatic mechanisms controlling intestinal epithelial proliferation/inflammation, differentiation, and programmed cell death, is the third most common malignant neoplasm worldwide. A number of promising targ...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Published: |
Asian Pacific Organization for Cancer Prevetion
2013
|
| _version_ | 1825947546632060928 |
|---|---|
| author | Pandurangan, Ashok Kumar Mohd Esa, Norhaizan |
| author_facet | Pandurangan, Ashok Kumar Mohd Esa, Norhaizan |
| author_sort | Pandurangan, Ashok Kumar |
| collection | UPM |
| description | Colorectal cancer (CRC), a complex multi-step process involving progressive disruption of homeostatic mechanisms controlling intestinal epithelial proliferation/inflammation, differentiation, and programmed cell death, is the third most common malignant neoplasm worldwide. A number of promising targets such as inducible nitric acid (iNOS), cyclooxygenase (COX)-2, NF-E2-related factor 2 (Nrf2), Wnt/β-catenin, Notch and apoptotic signaling have been identified by researchers as useful targets to prevent or therapeutically inhibit colon cancer development. In this review article, we aimed to explore the current targets available to eliminate colon cancer with an update of dietary and non-nutritional compounds that could be of potential use for interaction with regulatory molecules to prevent CRC. |
| first_indexed | 2024-03-06T08:15:02Z |
| format | Article |
| id | upm.eprints-29617 |
| institution | Universiti Putra Malaysia |
| last_indexed | 2024-03-06T08:15:02Z |
| publishDate | 2013 |
| publisher | Asian Pacific Organization for Cancer Prevetion |
| record_format | dspace |
| spelling | upm.eprints-296172015-12-08T00:44:49Z http://psasir.upm.edu.my/id/eprint/29617/ Dietary non-nutritive factors on molecular targets of colorectal cancer: an update Pandurangan, Ashok Kumar Mohd Esa, Norhaizan Colorectal cancer (CRC), a complex multi-step process involving progressive disruption of homeostatic mechanisms controlling intestinal epithelial proliferation/inflammation, differentiation, and programmed cell death, is the third most common malignant neoplasm worldwide. A number of promising targets such as inducible nitric acid (iNOS), cyclooxygenase (COX)-2, NF-E2-related factor 2 (Nrf2), Wnt/β-catenin, Notch and apoptotic signaling have been identified by researchers as useful targets to prevent or therapeutically inhibit colon cancer development. In this review article, we aimed to explore the current targets available to eliminate colon cancer with an update of dietary and non-nutritional compounds that could be of potential use for interaction with regulatory molecules to prevent CRC. Asian Pacific Organization for Cancer Prevetion 2013 Article NonPeerReviewed Pandurangan, Ashok Kumar and Mohd Esa, Norhaizan (2013) Dietary non-nutritive factors on molecular targets of colorectal cancer: an update. Asian Pacific Journal of Cancer Prevention, 14 (10). pp. 5543-5552. ISSN 1513-7368 http://www.apocpcontrol.org/page/apjcp_issues_view.php?pno=4940&gubun=p&s_search=&s_paper_vol=14&s_number33=10 10.7314/APJCP.2013.14.10.5543 |
| spellingShingle | Pandurangan, Ashok Kumar Mohd Esa, Norhaizan Dietary non-nutritive factors on molecular targets of colorectal cancer: an update |
| title | Dietary non-nutritive factors on molecular targets of colorectal cancer: an update |
| title_full | Dietary non-nutritive factors on molecular targets of colorectal cancer: an update |
| title_fullStr | Dietary non-nutritive factors on molecular targets of colorectal cancer: an update |
| title_full_unstemmed | Dietary non-nutritive factors on molecular targets of colorectal cancer: an update |
| title_short | Dietary non-nutritive factors on molecular targets of colorectal cancer: an update |
| title_sort | dietary non nutritive factors on molecular targets of colorectal cancer an update |
| work_keys_str_mv | AT panduranganashokkumar dietarynonnutritivefactorsonmoleculartargetsofcolorectalcanceranupdate AT mohdesanorhaizan dietarynonnutritivefactorsonmoleculartargetsofcolorectalcanceranupdate |