Chemical composition and antibacterial and cytotoxic activities of Allium hirtifolium Boiss
Allium hirtifolium Boiss. known as Persian shallot, is a spice used as a traditional medicine in Iran and, Mediterranean region. In this study, the chemical composition of the hydromethanolic extract of this plant was analyzed using GC/MS. The result showed that 9-hexadecenoic acid, 11,14-eicosadien...
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| Format: | Article |
| Language: | English |
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Hindawi Publishing Corporation
2013
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| Online Access: | http://psasir.upm.edu.my/id/eprint/29655/1/Chemical%20composition%20and%20antibacterial%20and%20cytotoxic%20activities%20of%20Allium%20hirtifolium%20Boiss.pdf |
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| author | Ismail, Salmiah Jalilian, Farid Azizi Talebpour, Amir Hossein Zargar, Mohsen Shameli, Kamyar Sekawi, Zamberi Jahanshiri, Fatemeh |
| author_facet | Ismail, Salmiah Jalilian, Farid Azizi Talebpour, Amir Hossein Zargar, Mohsen Shameli, Kamyar Sekawi, Zamberi Jahanshiri, Fatemeh |
| author_sort | Ismail, Salmiah |
| collection | UPM |
| description | Allium hirtifolium Boiss. known as Persian shallot, is a spice used as a traditional medicine in Iran and, Mediterranean region. In this study, the chemical composition of the hydromethanolic extract of this plant was analyzed using GC/MS. The result showed that 9-hexadecenoic acid, 11,14-eicosadienoic acid, and n-hexadecanoic acid are the main constituents. The antibacterial activity of the shallot extract was also examined by disk diffusion and microdilution broth assays. It was demonstrated that Persian shallot hydromethanolic extract was effective against 10 different species of pathogenic bacteria including methicillin resistant Staphylococcus aureus (MRSA), methicillin sensitive Staphylococcus aureus (MSSA), Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Escherichia coli, Escherichia coli O157:H7, Salmonella typhimurium, Proteus mirabilis, and Klebsiella pneumoniae. Specifically, the minimum concentration of the extract which inhibited bacterial growth (MIC values) was 1.88 mg/mL for most of the gram-positive bacteria. This concentration was not much different from the concentration that was safe for mammalian cells (1.50 mg/mL) suggesting that the hydromethanolic extract of Persian shallot may be a safe and strong antibacterial agent. |
| first_indexed | 2024-03-06T08:15:09Z |
| format | Article |
| id | upm.eprints-29655 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T08:15:09Z |
| publishDate | 2013 |
| publisher | Hindawi Publishing Corporation |
| record_format | dspace |
| spelling | upm.eprints-296552016-02-12T03:54:02Z http://psasir.upm.edu.my/id/eprint/29655/ Chemical composition and antibacterial and cytotoxic activities of Allium hirtifolium Boiss Ismail, Salmiah Jalilian, Farid Azizi Talebpour, Amir Hossein Zargar, Mohsen Shameli, Kamyar Sekawi, Zamberi Jahanshiri, Fatemeh Allium hirtifolium Boiss. known as Persian shallot, is a spice used as a traditional medicine in Iran and, Mediterranean region. In this study, the chemical composition of the hydromethanolic extract of this plant was analyzed using GC/MS. The result showed that 9-hexadecenoic acid, 11,14-eicosadienoic acid, and n-hexadecanoic acid are the main constituents. The antibacterial activity of the shallot extract was also examined by disk diffusion and microdilution broth assays. It was demonstrated that Persian shallot hydromethanolic extract was effective against 10 different species of pathogenic bacteria including methicillin resistant Staphylococcus aureus (MRSA), methicillin sensitive Staphylococcus aureus (MSSA), Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Escherichia coli, Escherichia coli O157:H7, Salmonella typhimurium, Proteus mirabilis, and Klebsiella pneumoniae. Specifically, the minimum concentration of the extract which inhibited bacterial growth (MIC values) was 1.88 mg/mL for most of the gram-positive bacteria. This concentration was not much different from the concentration that was safe for mammalian cells (1.50 mg/mL) suggesting that the hydromethanolic extract of Persian shallot may be a safe and strong antibacterial agent. Hindawi Publishing Corporation 2013 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/29655/1/Chemical%20composition%20and%20antibacterial%20and%20cytotoxic%20activities%20of%20Allium%20hirtifolium%20Boiss.pdf Ismail, Salmiah and Jalilian, Farid Azizi and Talebpour, Amir Hossein and Zargar, Mohsen and Shameli, Kamyar and Sekawi, Zamberi and Jahanshiri, Fatemeh (2013) Chemical composition and antibacterial and cytotoxic activities of Allium hirtifolium Boiss. BioMed Research International , 2013. art. no. 696835. pp. 1-8. ISSN 2314-6133; ESSN: 2314-6141 http://dx.doi.org/10.1155/2013/696835 10.1155/2013/696835 |
| spellingShingle | Ismail, Salmiah Jalilian, Farid Azizi Talebpour, Amir Hossein Zargar, Mohsen Shameli, Kamyar Sekawi, Zamberi Jahanshiri, Fatemeh Chemical composition and antibacterial and cytotoxic activities of Allium hirtifolium Boiss |
| title | Chemical composition and antibacterial and cytotoxic activities of Allium hirtifolium Boiss |
| title_full | Chemical composition and antibacterial and cytotoxic activities of Allium hirtifolium Boiss |
| title_fullStr | Chemical composition and antibacterial and cytotoxic activities of Allium hirtifolium Boiss |
| title_full_unstemmed | Chemical composition and antibacterial and cytotoxic activities of Allium hirtifolium Boiss |
| title_short | Chemical composition and antibacterial and cytotoxic activities of Allium hirtifolium Boiss |
| title_sort | chemical composition and antibacterial and cytotoxic activities of allium hirtifolium boiss |
| url | http://psasir.upm.edu.my/id/eprint/29655/1/Chemical%20composition%20and%20antibacterial%20and%20cytotoxic%20activities%20of%20Allium%20hirtifolium%20Boiss.pdf |
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