A phenylbutenoid dimer, cis-3-(3′,4′-dimethoxyphenyl)-4-[(E)-3′′′,4′′′-dimethoxystyryl] cyclohex-1-ene, exhibits apoptogenic properties in T-acute lymphoblastic leukemia cells via induction of p53-independent mitochondrial signalling pathway
The current study was designed to evaluate the in vitro cytotoxicity effect of a phenylbutenoid dimer, cis-3-(3′,4′-dimethoxyphenyl)-4-[(E)- 3‴,4‴-dimethoxystyryl]cyclohex-1-ene (ZC-B11) isolated from the rhizome of Zingiber cassumunar on various cancer cell line, and normal human blood mononuclear...
Main Authors: | Anasamy, Theebaa, Abdul, Ahmad Bustamam, Sukari, Mohd Aspollah, Abdelwahab, Siddig Ibrahim, Mohan, Syam, Kamalidehghan, Behnam, Azid, Mohd Zulkhairi, Muhammad Nadzri, Nabilah, Andas, A. Reenaa Joys, Beng, Ng Kuan, A. Hadi, A. Hamid, Rahman, Heshu Sulaiman |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Publishing Corporation
2013
|
Online Access: | http://psasir.upm.edu.my/id/eprint/30040/1/A%20phenylbutenoid%20dimer.pdf |
Similar Items
-
Induction of apoptosis by cis-3-(3',4'-dimethoxyphenyl)-4-[(E)-3"',4"'-dimethoxystyryl]cyclohex-1-ene isolated from the rhizome of Zingiber cassumunar roxb. on human T-lymphoblastic leukemia cell line, CEMss
by: Anasamy, Theebaa
Published: (2013) -
(<i>E</i>)-(1-(4-Ethoxycarbonylphenyl)-5-(3,4-dimethoxyphenyl)-3-(3,4-dimethoxystyryl)-2-pyrazoline: Synthesis, Characterization, DNA-Interaction, and Evaluation of Activity Against Drug-Resistant Cell Lines
by: Dimitris Matiadis, et al.
Published: (2020-01-01) -
Induction of selective cytotoxicity and apoptosis in human T4-lymphoblastoid cell line (CEMss) by boesenbergin a isolated from boesenbergia rotunda rhizomes involves mitochondrial pathway, activation of caspase 3 and G2/M phase cell cycle arrest
by: Ng, Kuan Beng, et al.
Published: (2013) -
trans-3-(3,4-Dimethoxyphenyl)-2-(4-nitrophenyl)prop-2-enenitrile
by: Tan, K.W., et al.
Published: (2010) -
Isoamyl (<i>E</i>)-3-(3,4-Dimethoxyphenyl)acrylate
by: Egar Pamela, et al.
Published: (2023-08-01)