Synthesis, characterization, and antimicrobial properties of copper nanoparticles

Copper nanoparticle synthesis has been gaining attention due to its availability. However, factors such as agglomeration and rapid oxidation have made it a difficult research area. In the present work, pure copper nanoparticles were prepared in the presence of a chitosan stabilizer through chemical...

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Main Authors: Usman, Muhammad Sani, El Zowalaty, Mohamed Ezzat, Shameli, Kamyar, Zainuddin, Norhazlin, Salama, Mohamed, Ibrahim, Nor Azowa
Format: Article
Language:English
English
Published: Dove Medical Press 2013
Online Access:http://psasir.upm.edu.my/id/eprint/30103/1/Synthesis%2C%20characterization%2C%20and%20antimicrobial%20properties%20of%20copper%20nanoparticles.pdf
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author Usman, Muhammad Sani
El Zowalaty, Mohamed Ezzat
Shameli, Kamyar
Zainuddin, Norhazlin
Salama, Mohamed
Ibrahim, Nor Azowa
author_facet Usman, Muhammad Sani
El Zowalaty, Mohamed Ezzat
Shameli, Kamyar
Zainuddin, Norhazlin
Salama, Mohamed
Ibrahim, Nor Azowa
author_sort Usman, Muhammad Sani
collection UPM
description Copper nanoparticle synthesis has been gaining attention due to its availability. However, factors such as agglomeration and rapid oxidation have made it a difficult research area. In the present work, pure copper nanoparticles were prepared in the presence of a chitosan stabilizer through chemical means. The purity of the nanoparticles was authenticated using different characterization techniques, including ultraviolet visible spectroscopy, transmission electron microscopy, X-ray diffraction, Fourier transform infrared spectroscopy, and field emission scanning electron microscopy. The antibacterial as well as antifungal activity of the nanoparticles were investigated using several microorganisms of interest, including methicillin-resistant Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Salmonella choleraesuis, and Candida albicans. The effect of a chitosan medium on growth of the microorganism was studied, and this was found to influence growth rate. The size of the copper nanoparticles obtained was in the range of 2-350 nm, depending on the concentration of the chitosan stabilizer.
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spelling upm.eprints-301032015-10-06T01:08:27Z http://psasir.upm.edu.my/id/eprint/30103/ Synthesis, characterization, and antimicrobial properties of copper nanoparticles Usman, Muhammad Sani El Zowalaty, Mohamed Ezzat Shameli, Kamyar Zainuddin, Norhazlin Salama, Mohamed Ibrahim, Nor Azowa Copper nanoparticle synthesis has been gaining attention due to its availability. However, factors such as agglomeration and rapid oxidation have made it a difficult research area. In the present work, pure copper nanoparticles were prepared in the presence of a chitosan stabilizer through chemical means. The purity of the nanoparticles was authenticated using different characterization techniques, including ultraviolet visible spectroscopy, transmission electron microscopy, X-ray diffraction, Fourier transform infrared spectroscopy, and field emission scanning electron microscopy. The antibacterial as well as antifungal activity of the nanoparticles were investigated using several microorganisms of interest, including methicillin-resistant Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Salmonella choleraesuis, and Candida albicans. The effect of a chitosan medium on growth of the microorganism was studied, and this was found to influence growth rate. The size of the copper nanoparticles obtained was in the range of 2-350 nm, depending on the concentration of the chitosan stabilizer. Dove Medical Press 2013-11-21 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/30103/1/Synthesis%2C%20characterization%2C%20and%20antimicrobial%20properties%20of%20copper%20nanoparticles.pdf Usman, Muhammad Sani and El Zowalaty, Mohamed Ezzat and Shameli, Kamyar and Zainuddin, Norhazlin and Salama, Mohamed and Ibrahim, Nor Azowa (2013) Synthesis, characterization, and antimicrobial properties of copper nanoparticles. International Journal of Nanomedicine, 8. pp. 4467-4479. ISSN 1176-9114; ESSN: 1178-2013 http://www.dovepress.com/international-journal-of-nanomedicine-i750-j5 10.2147/IJN.S50837 English
spellingShingle Usman, Muhammad Sani
El Zowalaty, Mohamed Ezzat
Shameli, Kamyar
Zainuddin, Norhazlin
Salama, Mohamed
Ibrahim, Nor Azowa
Synthesis, characterization, and antimicrobial properties of copper nanoparticles
title Synthesis, characterization, and antimicrobial properties of copper nanoparticles
title_full Synthesis, characterization, and antimicrobial properties of copper nanoparticles
title_fullStr Synthesis, characterization, and antimicrobial properties of copper nanoparticles
title_full_unstemmed Synthesis, characterization, and antimicrobial properties of copper nanoparticles
title_short Synthesis, characterization, and antimicrobial properties of copper nanoparticles
title_sort synthesis characterization and antimicrobial properties of copper nanoparticles
url http://psasir.upm.edu.my/id/eprint/30103/1/Synthesis%2C%20characterization%2C%20and%20antimicrobial%20properties%20of%20copper%20nanoparticles.pdf
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