A glucosinolate-rich extract of Japanese Daikon perturbs carcinogen-metabolizing enzyme systems in rat, being a potent inducer of hepatic glutathione S-transferase.
Purpose: Glucosinolates/isothiocyanates are an established class of naturally occurring chemopreventive agents, a principal mechanism of action being to limit the generation of genotoxic metabolites of chemical carcinogens, as a result of modulation of cytochrome P450 and phase II detoxification enz...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
Springer Verlag
2013
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| Online Access: | http://psasir.upm.edu.my/id/eprint/30433/1/A%20glucosinolate.pdf |