Well diffusion method for evaluation of antibacterial activity of copper phenyl fatty hydroxamate synthesized from canola and palm kernel oils.

Hydroxamic acids and their derivatives have low toxicities and show wide range of biological activities. Copper complexes of phenyl fatty hydroxamic acids (Cu-PFHs) were prepared in a biphasic organic / aqueous medium from phenyl fatty hydroxamic acids (PFHAs) and copper nitrate. The products were...

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Main Authors: Jahangirian, Hossein, Haron, Md Jelas, Ismail, Mohd Halim Shah, Rafiee Moghaddam, Roshanak, Afsah Hejri, Leili, Abdollahi, Yadollah, Rezayi, Majid, Vafaei, Nazanin
Format: Article
Language:English
Published: National Institute R and D of Materials Physics 2013
Online Access:http://psasir.upm.edu.my/id/eprint/30810/1/Well%20diffusion%20method%20for%20evaluation%20of%20antibacterial%20activity%20of%20copper%20phenyl%20fatty%20hydroxamate%20synthesized%20from%20canola%20and%20palm%20kernel%20oils.pdf
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author Jahangirian, Hossein
Haron, Md Jelas
Ismail, Mohd Halim Shah
Rafiee Moghaddam, Roshanak
Afsah Hejri, Leili
Abdollahi, Yadollah
Rezayi, Majid
Vafaei, Nazanin
author_facet Jahangirian, Hossein
Haron, Md Jelas
Ismail, Mohd Halim Shah
Rafiee Moghaddam, Roshanak
Afsah Hejri, Leili
Abdollahi, Yadollah
Rezayi, Majid
Vafaei, Nazanin
author_sort Jahangirian, Hossein
collection UPM
description Hydroxamic acids and their derivatives have low toxicities and show wide range of biological activities. Copper complexes of phenyl fatty hydroxamic acids (Cu-PFHs) were prepared in a biphasic organic / aqueous medium from phenyl fatty hydroxamic acids (PFHAs) and copper nitrate. The products were separated by decantation of organic phase from aqueous phase followed by evaporation of the solvent. Elemental analysis, UV-Vis spectra and FTIR spectra showed that Cu-PFHs were formed in the solution from the complexation of PFHAs and copper ion. The antibacterial activity of PFHAs and Cu-PFHs from canola and palm kernel oils were investigated against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) using well diffusion method. The results showed that Cu-PFHs have higher antibacterial activity compared to PFHAs. Antibacterial activity of Cu-PHAs from canola oil against E.coli was significantly higher than hloramphenicol and cefotaxime.
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spelling upm.eprints-308102015-10-05T07:49:45Z http://psasir.upm.edu.my/id/eprint/30810/ Well diffusion method for evaluation of antibacterial activity of copper phenyl fatty hydroxamate synthesized from canola and palm kernel oils. Jahangirian, Hossein Haron, Md Jelas Ismail, Mohd Halim Shah Rafiee Moghaddam, Roshanak Afsah Hejri, Leili Abdollahi, Yadollah Rezayi, Majid Vafaei, Nazanin Hydroxamic acids and their derivatives have low toxicities and show wide range of biological activities. Copper complexes of phenyl fatty hydroxamic acids (Cu-PFHs) were prepared in a biphasic organic / aqueous medium from phenyl fatty hydroxamic acids (PFHAs) and copper nitrate. The products were separated by decantation of organic phase from aqueous phase followed by evaporation of the solvent. Elemental analysis, UV-Vis spectra and FTIR spectra showed that Cu-PFHs were formed in the solution from the complexation of PFHAs and copper ion. The antibacterial activity of PFHAs and Cu-PFHs from canola and palm kernel oils were investigated against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) using well diffusion method. The results showed that Cu-PFHs have higher antibacterial activity compared to PFHAs. Antibacterial activity of Cu-PHAs from canola oil against E.coli was significantly higher than hloramphenicol and cefotaxime. National Institute R and D of Materials Physics 2013 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/30810/1/Well%20diffusion%20method%20for%20evaluation%20of%20antibacterial%20activity%20of%20copper%20phenyl%20fatty%20hydroxamate%20synthesized%20from%20canola%20and%20palm%20kernel%20oils.pdf Jahangirian, Hossein and Haron, Md Jelas and Ismail, Mohd Halim Shah and Rafiee Moghaddam, Roshanak and Afsah Hejri, Leili and Abdollahi, Yadollah and Rezayi, Majid and Vafaei, Nazanin (2013) Well diffusion method for evaluation of antibacterial activity of copper phenyl fatty hydroxamate synthesized from canola and palm kernel oils. Digest Journal of Nanomaterials and Biostructures, 8 (3). pp. 1263-1270. ISSN 1842-3582 http://www.chalcogen.ro/digest.html
spellingShingle Jahangirian, Hossein
Haron, Md Jelas
Ismail, Mohd Halim Shah
Rafiee Moghaddam, Roshanak
Afsah Hejri, Leili
Abdollahi, Yadollah
Rezayi, Majid
Vafaei, Nazanin
Well diffusion method for evaluation of antibacterial activity of copper phenyl fatty hydroxamate synthesized from canola and palm kernel oils.
title Well diffusion method for evaluation of antibacterial activity of copper phenyl fatty hydroxamate synthesized from canola and palm kernel oils.
title_full Well diffusion method for evaluation of antibacterial activity of copper phenyl fatty hydroxamate synthesized from canola and palm kernel oils.
title_fullStr Well diffusion method for evaluation of antibacterial activity of copper phenyl fatty hydroxamate synthesized from canola and palm kernel oils.
title_full_unstemmed Well diffusion method for evaluation of antibacterial activity of copper phenyl fatty hydroxamate synthesized from canola and palm kernel oils.
title_short Well diffusion method for evaluation of antibacterial activity of copper phenyl fatty hydroxamate synthesized from canola and palm kernel oils.
title_sort well diffusion method for evaluation of antibacterial activity of copper phenyl fatty hydroxamate synthesized from canola and palm kernel oils
url http://psasir.upm.edu.my/id/eprint/30810/1/Well%20diffusion%20method%20for%20evaluation%20of%20antibacterial%20activity%20of%20copper%20phenyl%20fatty%20hydroxamate%20synthesized%20from%20canola%20and%20palm%20kernel%20oils.pdf
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