Antibacterial, cytotoxic studies and characterization of some newly synthesized symmetrical N 3, N 3 ′ -bis(disubstituted)isophthalyl- bis(thioureas) and their Cu(II) and Ni(II) complexes
A series of some novel ,-bis(disubstituted)isophthalyl-bis(thioureas) compounds with general formula [C6H4 {CONHCSNHR}2], where R = 2-ClC6H4S (L1), 3,5-(Cl)2C6H3 (L2), 2,4-(Cl)2C6H3 (L3), 2,5-(Cl)2C6H3 (L4), and 2-NH2C6H4 (L5), and their Cu(II) and Ni(II) complexes (C1–C10) have been synthesized. Th...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English English |
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Hindawi Publishing Corporation
2013
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| Online Access: | http://psasir.upm.edu.my/id/eprint/30814/1/Antibacterial.pdf |
| _version_ | 1796971816557740032 |
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| author | Jamil, Muhammad Zubair, Muhammad Farid, Muhammad Asim Rashid, Umer Rasool, Nasir Islam, Saiful |
| author_facet | Jamil, Muhammad Zubair, Muhammad Farid, Muhammad Asim Rashid, Umer Rasool, Nasir Islam, Saiful |
| author_sort | Jamil, Muhammad |
| collection | UPM |
| description | A series of some novel ,-bis(disubstituted)isophthalyl-bis(thioureas) compounds with general formula [C6H4 {CONHCSNHR}2], where R = 2-ClC6H4S (L1), 3,5-(Cl)2C6H3 (L2), 2,4-(Cl)2C6H3 (L3), 2,5-(Cl)2C6H3 (L4), and 2-NH2C6H4 (L5), and their Cu(II) and Ni(II) complexes (C1–C10) have been synthesized. These compounds (L1–L5) and their metal(II) complexes (C1–C10) have been characterized by elemental analysis, infrared spectroscopy, 1H NMR and 13C NMR spectroscopy, magnetic moments, and electronic spectral measurements. The ligands are coordinated to metal atom in a bidentate pattern producing a neutral complex of the type [ML]2. These compounds (L1–L5) and their metal(II) complexes (C1–C10) were also screened for their antibacterial and cytotoxic activities. |
| first_indexed | 2024-03-06T08:18:42Z |
| format | Article |
| id | upm.eprints-30814 |
| institution | Universiti Putra Malaysia |
| language | English English |
| last_indexed | 2024-03-06T08:18:42Z |
| publishDate | 2013 |
| publisher | Hindawi Publishing Corporation |
| record_format | dspace |
| spelling | upm.eprints-308142015-10-05T01:29:00Z http://psasir.upm.edu.my/id/eprint/30814/ Antibacterial, cytotoxic studies and characterization of some newly synthesized symmetrical N 3, N 3 ′ -bis(disubstituted)isophthalyl- bis(thioureas) and their Cu(II) and Ni(II) complexes Jamil, Muhammad Zubair, Muhammad Farid, Muhammad Asim Rashid, Umer Rasool, Nasir Islam, Saiful A series of some novel ,-bis(disubstituted)isophthalyl-bis(thioureas) compounds with general formula [C6H4 {CONHCSNHR}2], where R = 2-ClC6H4S (L1), 3,5-(Cl)2C6H3 (L2), 2,4-(Cl)2C6H3 (L3), 2,5-(Cl)2C6H3 (L4), and 2-NH2C6H4 (L5), and their Cu(II) and Ni(II) complexes (C1–C10) have been synthesized. These compounds (L1–L5) and their metal(II) complexes (C1–C10) have been characterized by elemental analysis, infrared spectroscopy, 1H NMR and 13C NMR spectroscopy, magnetic moments, and electronic spectral measurements. The ligands are coordinated to metal atom in a bidentate pattern producing a neutral complex of the type [ML]2. These compounds (L1–L5) and their metal(II) complexes (C1–C10) were also screened for their antibacterial and cytotoxic activities. Hindawi Publishing Corporation 2013-09-09 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/30814/1/Antibacterial.pdf Jamil, Muhammad and Zubair, Muhammad and Farid, Muhammad Asim and Rashid, Umer and Rasool, Nasir and Islam, Saiful (2013) Antibacterial, cytotoxic studies and characterization of some newly synthesized symmetrical N 3, N 3 ′ -bis(disubstituted)isophthalyl- bis(thioureas) and their Cu(II) and Ni(II) complexes. Journal of Chemistry, 2013. art. no. 789743. pp. 1-8. ISSN 2090-9063; ESSN: 2090-9071 http://www.hindawi.com/journals/jchem/2013/789743/ 10.1155/2013/789743 English |
| spellingShingle | Jamil, Muhammad Zubair, Muhammad Farid, Muhammad Asim Rashid, Umer Rasool, Nasir Islam, Saiful Antibacterial, cytotoxic studies and characterization of some newly synthesized symmetrical N 3, N 3 ′ -bis(disubstituted)isophthalyl- bis(thioureas) and their Cu(II) and Ni(II) complexes |
| title | Antibacterial, cytotoxic studies and characterization of some newly synthesized symmetrical N 3, N 3 ′ -bis(disubstituted)isophthalyl- bis(thioureas) and their Cu(II) and Ni(II) complexes |
| title_full | Antibacterial, cytotoxic studies and characterization of some newly synthesized symmetrical N 3, N 3 ′ -bis(disubstituted)isophthalyl- bis(thioureas) and their Cu(II) and Ni(II) complexes |
| title_fullStr | Antibacterial, cytotoxic studies and characterization of some newly synthesized symmetrical N 3, N 3 ′ -bis(disubstituted)isophthalyl- bis(thioureas) and their Cu(II) and Ni(II) complexes |
| title_full_unstemmed | Antibacterial, cytotoxic studies and characterization of some newly synthesized symmetrical N 3, N 3 ′ -bis(disubstituted)isophthalyl- bis(thioureas) and their Cu(II) and Ni(II) complexes |
| title_short | Antibacterial, cytotoxic studies and characterization of some newly synthesized symmetrical N 3, N 3 ′ -bis(disubstituted)isophthalyl- bis(thioureas) and their Cu(II) and Ni(II) complexes |
| title_sort | antibacterial cytotoxic studies and characterization of some newly synthesized symmetrical n 3 n 3 bis disubstituted isophthalyl bis thioureas and their cu ii and ni ii complexes |
| url | http://psasir.upm.edu.my/id/eprint/30814/1/Antibacterial.pdf |
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