Recombinant vectors for the treatment of tumor cells
The present invention relates to gene therapy for the treatment of tumors. Accordingly, the present invention discloses recombinant vector expression constructs (vectors) which confer infectivity, replication, transcription, or any combination thereof when the construct is introduced into cells eith...
| Main Authors: | , , , |
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| Format: | Patent |
| Published: |
2010
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| Summary: | The present invention relates to gene therapy for the treatment of tumors. Accordingly, the present invention discloses recombinant vector expression constructs (vectors) which confer infectivity, replication, transcription, or any combination thereof when the construct is introduced into cells either in vitro or in vivo, with or without a viral particle. The recombinant vector constructs are engineered to express a combination of two heterologous nucleotide sequence(s), especially genes encoding an infectious bursal disease polypeptide (VP2) combined with another nucleic acid molecule encoding a chicken anemia virus polypeptide (VP3) or murine endostatin. |
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