Biomarkers in cancer: an overview
Traditional tumour markers such as carcinoembryonic antigen (CEA) that have been used for screening gastrointestinal neoplasia for many years are not specific. However, these markers are useful after diagnosis to monitor progress of the disease and recurrence. New biomarkers are constantly being dev...
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| Format: | Article |
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Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
2008
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| _version_ | 1825948164298899456 |
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| author | Seow, Heng Fong |
| author_facet | Seow, Heng Fong |
| author_sort | Seow, Heng Fong |
| collection | UPM |
| description | Traditional tumour markers such as carcinoembryonic antigen (CEA) that have been used for screening gastrointestinal neoplasia for many years are not specific. However, these markers are useful after diagnosis to monitor progress of the disease and recurrence. New biomarkers are constantly being developed to identify individuals with risk of cancer for early detection, to determine prognosis, to detect recurrence, to predict drug responses and to monitor response to treatment. There are several issues involved in the discovery of biomarkers and their development for clinical applications. This article provides a basic overview of the classes of biomarkers, the current status of molecular profiling and discusses the opportunities as well as challenges ahead to improve biomarker development. |
| first_indexed | 2024-03-06T08:24:30Z |
| format | Article |
| id | upm.eprints-32884 |
| institution | Universiti Putra Malaysia |
| last_indexed | 2024-03-06T08:24:30Z |
| publishDate | 2008 |
| publisher | Faculty of Medicine and Health Sciences, Universiti Putra Malaysia |
| record_format | dspace |
| spelling | upm.eprints-328842015-10-07T06:49:58Z http://psasir.upm.edu.my/id/eprint/32884/ Biomarkers in cancer: an overview Seow, Heng Fong Traditional tumour markers such as carcinoembryonic antigen (CEA) that have been used for screening gastrointestinal neoplasia for many years are not specific. However, these markers are useful after diagnosis to monitor progress of the disease and recurrence. New biomarkers are constantly being developed to identify individuals with risk of cancer for early detection, to determine prognosis, to detect recurrence, to predict drug responses and to monitor response to treatment. There are several issues involved in the discovery of biomarkers and their development for clinical applications. This article provides a basic overview of the classes of biomarkers, the current status of molecular profiling and discusses the opportunities as well as challenges ahead to improve biomarker development. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2008-01 Article PeerReviewed Seow, Heng Fong (2008) Biomarkers in cancer: an overview. Malaysian Journal of Medicine and Health Sciences, 4 (1). pp. 23-32. ISSN 1675-8544 |
| spellingShingle | Seow, Heng Fong Biomarkers in cancer: an overview |
| title | Biomarkers in cancer: an overview |
| title_full | Biomarkers in cancer: an overview |
| title_fullStr | Biomarkers in cancer: an overview |
| title_full_unstemmed | Biomarkers in cancer: an overview |
| title_short | Biomarkers in cancer: an overview |
| title_sort | biomarkers in cancer an overview |
| work_keys_str_mv | AT seowhengfong biomarkersincanceranoverview |