A composition for treating leukemia

A composition for treating leukemia

The present invention relates to a composition for treating leukemia. The composition comprises of effective amount of zerumbone and a pharmaceutically acceptable carrier characterized in that the carrier is a nanostructure lipid carrier. The composition is safe for administration in human body and...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Abdullah, Rasedee, Rahman, Heshu Sulaiman, Abdul, Ahmad Bustamam, How, Chee Wun, Yeap, Swee Keong
Format:	Patent
Udgivet:	2013

Lignende værker

Zerumbone induces apoptosis in human acute leukemia Jurkat T-cell line
af: Rahman, Heshu Sulaiman, et al.
Udgivet: (2012)

Zerumbone-loaded nanostructured lipid carrier induces G2/M cell cycle arrest and apoptosis via mitochondrial pathway in a human lymphoblastic leukemia cell line
af: Rahman, Heshu Sulaiman, et al.
Udgivet: (2014)

Biomedical properties of a natural dietary plant metabolite, zerumbone, in cancer therapy and chemoprevention trials
af: Rahman, Heshu Sulaiman, et al.
Udgivet: (2014)

Biomedical properties of a natural dietary plant metabolite, zerumbone, in cancer therapy and chemoprevention trail
af: Rahman, Heshu Sulaiman, et al.
Udgivet: (2014)

Zerumbone-loaded nanostructured lipid carriers: preparation, characterization, and antileukemic effect
af: Rahman, Heshu Sulaiman, et al.
Udgivet: (2013)

Zerumbone induces apoptosis in Jurkat T-cell line via activation of caspase 3 and caspase 9
af: Rahman, Heshu Sulaiman, et al.
Udgivet: (2012)

Antileukemic effect of zerumbone-loaded nanostructured lipid carrier in WEHI-3B cell-induced murine leukemia model
af: Rahman, Heshu Sulaiman, et al.
Udgivet: (2015)

Apoptosis induction in human leukemia cell lines by gold nanoparticles synthesized using the green biosynthetic approach
af: Namvar, Farideh, et al.
Udgivet: (2015)

Cytotoxicty of zerumbone against liver cancer cell lines (HepG2) via apoptosis activity
af: Abdul Samad, Nozlena, et al.
Udgivet: (2014)

Antiproliferative Efficacy of Zerumbone-Loaded Nanostructured Lipid Carrier in BALB/C Mice Model of Breast Cancer
af: Rahman, Heshu Sulaiman, et al.
Udgivet: (2014)

Zerumbone induces G2/M cell cycle arrest and apoptosis via mitochondrial pathway in Jurkat cell line
af: Rahman, Heshu Sulaiman, et al.
Udgivet: (2014)

Characterization and toxicity of citral incorporated with nanostructured lipid carrier
af: Mohammed Alitheen, Noorjahan Banu, et al.
Udgivet: (2018)

In vitro cytotoxicity and anticancer effects of citral nanostructured lipid carrier on MDA MBA-231 human breast cancer cells
af: Nordin, Noraini, et al.
Udgivet: (2019)

Acute toxicity study of zerumbone-loaded nanostructured lipid carrier on BALB/c mice model
af: Rahman, Heshu Sulaiman, et al.
Udgivet: (2014)

Characterization and cytotoxicty of nanostructured lipid carriers formulated with olive oil, hydrogenated palm oil and polysorbate 80.
af: How, Chee Wun, et al.
Udgivet: (2013)

Physicochemical properties of nanostructured lipid carriers as colloidal carrier system stabilized with polysorbate 20 and polysorbate 80
af: How, Chee Wun, et al.
Udgivet: (2011)

Clausenidin induces caspase-dependent apoptosis in colon cancer
af: Waziri, Peter M., et al.
Udgivet: (2016)

Zerumbone nanoparticle preparation and characterization
af: Rahman, Heshu, et al.
Udgivet: (2015)

Water extract of brewers' rice induces apoptosis in human colorectal cancer cells via activation of caspase-3 and caspase-8 and downregulates the Wnt/β-catenin downstream signaling pathway in brewers' rice-treated rats with azoxymethane-induced colon carcinogenesis
af: Tan, Bee Ling, et al.
Udgivet: (2015)

Tamoxifen-loaded nanostructured lipid carrier as a drug delivery system: characterization, stability assessment and cytotoxicity
af: How, Chee Wun, et al.
Udgivet: (2013)

Zerumbone-loaded nanostructured lipid carrier induces apoptosis of canine mammary Adenocarcinoma cells
af: Foong, Jia Ning, et al.
Udgivet: (2018)

Antitumor and anti-metastatic effects of citral loaded nanostructured lipid carrier in 4T1 induced breast cancer mouse model
af: Nordin, Noraini, et al.
Udgivet: (2020)

In vivo anti-tumor effects of citral on 4T1 breast cancer cells via induction of apoptosis and downregulation of aldehyde dehydrogenase activity
af: Nigjeh, Siyamak Ebrahimi, et al.
Udgivet: (2019)

Clausenidin from Clausena excavata induces apoptosis in hepG2 cells via the mitochondrial pathway
af: Waziri, Peter M., et al.
Udgivet: (2016)

Thymoquinone loaded nanostructured lipid carriers (TQ-NLC) and uses thereof
af: Saiful Yazan, Latifah, et al.
Udgivet: (2012)

Effect of recombinant human erythropoietin and bovine lactoferrin on canine mammary gland tumor cell
af: Kiew, Cai Xuan, et al.
Udgivet: (2010)

Novel gold nanoparticles reduced by Sargassum glaucescens: preparation, characterization and anticancer activity
af: Ajdari, Zahra, et al.
Udgivet: (2016)

Methods and compositions for inhibiting cancer cell growth
af: Mohamed, Suhaila, et al.
Udgivet: (2014)

Preparation and characterization of self nano-emulsifying drug delivery system loaded with citraland its antiproliferative effect on colorectal cells in vitro
af: Mohd Izham, Mira Nadiah, et al.
Udgivet: (2019)

Extracts of Typhonium flagelliforme tubers for treatment of leukemia.
af: Abdul, Ahmad Bustamam, et al.
Udgivet: (2010)

Effect of hypoxia on the response of canine mammary gland tumor cells to bovine lactoferrin, doxorubucin and recombinant human erythropoietin
af: Tan, Felina Peck Yen, et al.
Udgivet: (2010)

Cytotoxic effects of bio-synthesized zinc oxide nanoparticles on murine cell lines
af: Namvar, Farideh, et al.
Udgivet: (2014)

Crude extracts, flavokawain B and alpinetin compounds from the rhizome of Alpinia mutica induce cell death via UCK2 enzyme inhibition and in turn reduce 18S rRNA biosynthesis in HT-29 cells
af: Malami, Ibrahim, et al.
Udgivet: (2017)

Cytotoxic effect of magnetic iron oxide nanoparticles synthesized via seaweed aqueous extract
af: Namvar, Farideh, et al.
Udgivet: (2014)

Immunomodulatory Effects of Rhaphidophora Korthalsii Methanol Extract on Natural Killer Cell Activation and Cytolytic Activity
af: Yeap, Swee Keong
Udgivet: (2010)

Artonin E induces p53-independent g1 cell cycle arrest and apoptosis through ROS-mediated mitochondrial pathway and livin suppression in MCF-7 cell
af: Etti, Imaobong Christopher, et al.
Udgivet: (2017)

Physicochemical characterization, cytotoxic effect and toxicity evaluation of nanostructured lipid carrier loaded with eucalyptol
af: Mira Nadiah Mohd Izham, et al.
Udgivet: (2021)

Cytotoxic effect of betulinic acid and betulinic acid acetate isolated from Melaleuca cajuput on human myeloid leukemia (HL-60) cell line
af: Faujan, Nur Hana, et al.
Udgivet: (2010)

Novel drug delivery systems for loading of natural plant extracts and their biomedical applications
af: Rahman, Heshu Sulaiman, et al.
Udgivet: (2020)

Lipid nanoparticles in anti-breast cancer drug delivery systems and drug-membrane interactions
af: How, Chee Wun
Udgivet: (2014)